Evidence map›Paper›PMID 27605308›Full record

ArticleLangmuir : the ACS journal of surfaces and colloids2016

Plasmon-Enhanced Photocleaving Dynamics in Colloidal MicroRNA-Functionalized Silver Nanoparticles Monitored with Second Harmonic Generation.

Raju R Kumal, Mohammad Abu-Laban, Corey R Landry, Blake Kruger, Zhenyu Zhang, Daniel J Hayes, Louis H Haber

Abstract read
In one paragraph

Article in Langmuir : the ACS journal of surfaces and colloids, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Growth Dynamics of Colloidal Silver-Gold Core-Shell Nanoparticles Studied byThe journal of physical chemistry. C, Nanomaterials and interfaces · 2021
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Raju R Kumal
Mohammad Abu-Laban
Corey R Landry
Blake Kruger
Zhenyu Zhang
Daniel J HayesDepartment of Biomedical Engineering, the Pennsylvania State University , University Park, Pennsylvania 16802, United States.
Louis H Haber
Pennsylvania State University · US

Funding

Spatiotemporal Modulation of Osteogenesis in a 3-D Stromal/Stem Cell ModelR01DE024790 · NIDCR · PENNSYLVANIA STATE UNIVERSITY, THE · PI HAYES, DANIEL J. · 2015 to 2019
$1.7M
NIDCR NIH HHS R01 DE024790
6 · The paper itself

Abstract

The photocleaving dynamics of colloidal microRNA-functionalized nanoparticles are studied using time-dependent second harmonic generation (SHG) measurements. Model drug-delivery systems composed of oligonucleotides attached to either silver nanoparticles or polystyrene nanoparticles using a nitrobenzyl photocleavable linker are prepared and characterized. The photoactivated controlled release is observed to be most efficient on resonance at 365 nm irradiation, with pseudo-first-order rate constants that are linearly proportional to irradiation powers. Additionally, silver nanoparticles show a 6-fold plasmon enhancement in photocleaving efficiency over corresponding polystyrene nanoparticle rates, while our previous measurements on gold nanoparticles show a 2-fold plasmon enhancement compared to polystyrene nanoparticles. Characterizations including extinction spectroscopy, electrophoretic mobility, and fluorimetry measurements confirm the analysis from the SHG results. The real-time SHG measurements are shown to be a highly sensitive method for investigating plasmon-enhanced photocleaving dynamics in model drug delivery systems.

Indexed as

Drug CarriersDrug LiberationKineticsLightMetal NanoparticlesMicroRNAsPolystyrenesSecond Harmonic Generation MicroscopySilverSurface Plasmon ResonanceDrug CarriersMicroRNAsPolystyrenesSilver

Identifiers

PMID27605308
PMCPMC5124014
OpenAlexW2515914305

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.