ArticleThe New phytologist2017
APETALA2 antagonizes the transcriptional activity of AGAMOUS in regulating floral stem cells in Arabidopsis thaliana.
Article in The New phytologist, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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48 citing papers in PubMed.
- Insights into Candidate Pathways Associated with Multi-Pistil Formation in Chinese Chestnut (Biology · 2026Article
- Transposons drove the evolution of a male sex-determining gene from a female gene with deep introgression across cichlids.Science advances · 2026Article
- Article
- The Role of CRABS CLAW Transcription Factor in Floral Organ Development in Plants.International journal of molecular sciences · 2025Review
- VvWUS increases carpel number by upregulating VvAG2 expression in grapevine.Plant cell reports · 2025Article
- Identification and characterization of two APETALA2 homolog genes in lotus (Nelumbo nucifera) involved in sepal and petal development.BMC plant biology · 2024Article
- Coordination of shoot apical meristem shape and identity by APETALA2 during floral transition in Arabidopsis.Nature communications · 2024Article
- Transcriptomic and metabolomic profiling reveals molecular regulatory network involved in flower development and phenotypic changes in two3 Biotech · 2024Article
- SlCRCa is a key D-class gene controlling ovule fate determination in tomato.Plant biotechnology journal · 2024Article
- APETALA2-like Floral Homeotic Protein Up-RegulatingInternational journal of molecular sciences · 2024Article
- The transcription factor RhMYB17 regulates the homeotic transformation of floral organs in rose (Rosa hybrida) under cold stress.Journal of experimental botany · 2024Article
- The APETALA2-MYBL2 module represses proanthocyanidin biosynthesis by affecting formation of the MBW complex in seeds of Arabidopsis thaliana.Plant communications · 2024Article
- Antagonistic regulation of target genes by the SISTER OF TM3-JOINTLESS2 complex in tomato inflorescence branching.The Plant cell · 2023Article
- Tomato APETALA2 family member SlTOE1 regulates inflorescence branching by repressing SISTER OF TM3.Plant physiology · 2023Article
- APETALA2 is involved in ABA signaling during seed germination.Plant molecular biology · 2023Article
- The double flower variant of yellowhorn is due to a LINE1 transposon-mediated insertion.Plant physiology · 2023Article
- Genetic Screens for Floral Mutants in Arabidopsis thaliana: Enhancers and Suppressors.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Flower Development in Arabidopsis.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Chlorate-induced molecular floral transition revealed by transcriptomes.Open life sciences · 2023Article
- Less is more: natural variation disrupting a miR172 gene at the di locus underlies the recessive double-flower trait in peach (P. persica L. Batsch).BMC plant biology · 2022Article
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9 authors.
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Abstract
APETALA2 (AP2) is best known for its function in the outer two floral whorls, where it specifies the identities of sepals and petals by restricting the expression of AGAMOUS (AG) to the inner two whorls in Arabidopsis thaliana. Here, we describe a role of AP2 in promoting the maintenance of floral stem cell fate, not by repressing AG transcription, but by antagonizing AG activity in the center of the flower. We performed a genetic screen with ag-10 plants, which exhibit a weak floral determinacy defect, and isolated a mutant with a strong floral determinacy defect. This mutant was found to harbor another mutation in AG and was named ag-11. We performed a genetic screen in the ag-11 background to isolate mutations that suppress the floral determinacy defect. Two suppressor mutants were found to harbor mutations in AP2. While AG is known to shut down the expression of the stem cell maintenance gene WUSCHEL (WUS) to terminate floral stem cell fate, AP2 promotes the expression of WUS. AP2 does not repress the transcription of AG in the inner two whorls, but instead counteracts AG activity.
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