ArticleHypertension research : official journal of the Japanese Society of Hypertension2017
Arterial stiffness and decline of renal function in a primary care population.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 39 citations in OpenAlex.
- Time-dependent association between progression of arterial stiffness and risk of incident chronic kidney disease: a cohort study in China.Diabetologia · 2026Article
- Aortic Stiffness Can be Predicted From Different eGFR Formulas With Long Follow-Up in the Malmö Diet Cancer Study.Angiology · 2025Article
- Estimated pulse wave velocity as a potential predictor of albuminuria in hypertension.Frontiers in medicine · 2025Article
- Multiple and large simple renal cysts are associated with glomerular filtration rate decline: a cross-sectional study of Chinese population.European journal of medical research · 2024Article
- Aortic Stiffness: A Major Risk Factor for Multimorbidity in the Elderly.Journal of clinical medicine · 2023Review
- Correlation among cystatin C, homocysteine and arteriosclerosis indexes in patients with chronic kidney disease.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021Article
- Predictive value of cardio-ankle vascular index for the risk of end-stage renal disease.Clinical kidney journal · 2021Article
- Serum leptin levels are positively associated with aortic stiffness in patients with chronic kidney disease stage 3-5.Adipocyte · 2020Article
- Interrelationship among Obstructive Sleep Apnea, Renal Function and Survival: A Cohort Study.International journal of environmental research and public health · 2020Observational
- Arterial Stiffness Predicts Rapid Decline in Glomerular Filtration Rate Among Patients with High Cardiovascular Risks.Journal of atherosclerosis and thrombosis · 2020Article
- Peripheral Arterial Stiffness Increases the Risk of Progression of Renal Disease in Type 2 Diabetic Patients.Frontiers in medicine · 2020Article
- The Association of Fractional Pulse Pressure with Acute Kidney Injury in Patients Undergoing Coronary Intervention due to ST-Segment Elevated Myocardial Infarction.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2020Article
- Simple renal cysts are associated with increased arterial stiffness in a Taiwanese population.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- Estimated glomerular filtration rate and arterial stiffness in Japanese population: a secondary analysis based on a cross-sectional study.Lipids in health and disease · 2019Article
- Differential effects of arterial stiffness and fluid overload on blood pressure according to renal function in patients at risk for cardiovascular disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Observational
- Healthy aging and carotid performance: strain measures and β-stiffness index.Hypertension research : official journal of the Japanese Society of Hypertension · 2018Article
- Arterial stiffness in end-stage renal disease-pathogenesis, clinical epidemiology, and therapeutic potentials.Hypertension research : official journal of the Japanese Society of Hypertension · 2018Review
- Kidney Appreciates Stable Blood Pressure.American journal of hypertension · 2018Article
- Elevated pulse amplification in hypertensive patients with advanced kidney disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2018Article
- Relationship between brachial-ankle and heart-femoral pulse wave velocities and the rapid decline of kidney function.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arterial stiffness is an important pathophysiological factor linking cardiovascular disease and kidney disease. Controversy exists as to whether arterial stiffness causes renal function decline, or kidney dysfunction leads to stiffening or whether the association is mutual. We aimed to investigate the longitudinal association between arterial stiffness and annual rate of renal function decline. We prospectively investigated in a primary care population whether carotid-femoral pulse wave velocity (PWV) was associated with estimated glomerular filtration rate (eGFR) and annual decline in eGFR in participants aged ⩾40 years without overt kidney disease. Baseline data on PWV and eGFR were available for 587 participants; follow-up measurements with a mean duration of 5.6 years were available for 222 patients. PWV, female gender and mean arterial pressure were independently associated with eGFR at baseline, although age confounded this association. More importantly, baseline PWV, age and eGFR were independent predictors of renal function decline. Stratification for age showed that the effect of PWV on rate of eGFR decline was amplified with advancing age. On the other hand, baseline eGFR did not determine annual change in PWV, suggesting a unidirectional association between arterial stiffness and eGFR. Arterial stiffness amplifies age-related renal function decline, suggesting that arterial stiffness plays a causal role in the development of renal damage, at least at later stages of age-related renal function decline, possibly through impaired renal autoregulation and increased arterial blood pressure pulsatility.
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