Evidence map›Paper›PMID 27604036›Full record

ArticleOrganic & biomolecular chemistry2016

The Bull-James assembly as a chiral auxiliary and shift reagent in kinetic resolution of alkyne amines by the CuAAC reaction.

William D G Brittain, Brette M Chapin, Wenlei Zhai, Vincent M Lynch, Benjamin R Buckley, Eric V Anslyn, John S Fossey

Abstract read
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In one paragraph

Article in Organic & biomolecular chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

William D G BrittainSchool of Chemistry, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, UK. j.s.fossey@bham.ac.uk and Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, USA. anslyn@austin.utexas.edu.ORCID http://orcid.org/0000-0002-2876-5895
Brette M ChapinSchool of Chemistry, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, UK. j.s.fossey@bham.ac.uk and Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, USA. anslyn@austin.utexas.edu.
Wenlei ZhaiSchool of Chemistry, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, UK. j.s.fossey@bham.ac.uk and Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, USA. anslyn@austin.utexas.edu.
Vincent M LynchDepartment of Chemistry, The University of Texas at Austin, Austin, Texas 78712, USA. anslyn@austin.utexas.edu.
Benjamin R BuckleyDepartment of Chemistry, Loughborough University, Loughborough, Leicestershire, LE11 3TU, UK.
Eric V AnslynDepartment of Chemistry, The University of Texas at Austin, Austin, Texas 78712, USA. anslyn@austin.utexas.edu.
John S FosseySchool of Chemistry, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, UK. j.s.fossey@bham.ac.uk.ORCID http://orcid.org/0000-0002-2626-5117

Funding

Refining & Implementing Supramolecular Methods for HTS of EE & ConcentrationR01GM077437 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI ANSLYN, ERIC V. · 2006 to 2021
$3.4M
NIGMS NIH HHS R01 GM077437
6 · The paper itself

Abstract

The Bull-James boronic acid assembly is used simultaneously as a chiral auxiliary for kinetic resolution and as a chiral shift reagent for in situ enantiomeric excess (ee) determination by

Identifiers

PMID27604036
PMCPMC5121074

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.