Evidence map›Paper›PMID 27603954›Full record

ArticleFood additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment2017

Evaluation of the efficacy, acceptability and palatability of calcium montmorillonite clay used to reduce aflatoxin B1 dietary exposure in a crossover study in Kenya.

Abigael O Awuor, Ellen Yard, Johnni H Daniel, Collen Martin, Christine Bii, Amelia Romoser, Elvis Oyugi, Sarah Elmore, Samwel Amwayi, John Vulule and 5 more

Open access · greenAbstract read
In one paragraph

Article in Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
11.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Article
  3. Role of theToxins · 2025
    Article
  4. Review
  5. NutriClayJournal of food protection · 2025
    Article
  6. LGG/LAC-MMT combination mitigates AFBFrontiers in veterinary science · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Evaluation of acute and chronic exposure to aflatoxin BEnvironmental science and pollution research international · 2020
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Development of enterosorbents that can be added to food and water to reduce toxin exposures during disasters.Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes · 2019
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Abigael O Awuora US Centers for Disease Control and Prevention (CDC), Kenya , Center for Global Health , Nairobi , Kenya.
Ellen Yardb US Centers for Disease Control and Prevention (CDC) , National Center for Environmental Health , Atlanta , GA , USA.
Johnni H Danielb US Centers for Disease Control and Prevention (CDC) , National Center for Environmental Health , Atlanta , GA , USA.
Collen Martinb US Centers for Disease Control and Prevention (CDC) , National Center for Environmental Health , Atlanta , GA , USA.
Christine Biic Centre for Microbiology Research Nairobi , Kenya Medical Research Institute , Kisumu , Kenya.
Amelia Romoserd College of Veterinary Medicine and Biomedical Sciences , Texas A&M University , College Station , TX , USA.
Elvis Oyugie Ministry of Health , Field Epidemiology and Laboratory Training Program , Nairobi , Kenya.
Sarah Elmored College of Veterinary Medicine and Biomedical Sciences , Texas A&M University , College Station , TX , USA.
Samwel Amwayie Ministry of Health , Field Epidemiology and Laboratory Training Program , Nairobi , Kenya.
John Vululef Centre for Public Health Research , Kenya Medical Research Institute , Kisumu , Kenya.
Nicholas C Zitomerb US Centers for Disease Control and Prevention (CDC) , National Center for Environmental Health , Atlanta , GA , USA.
Michael E Rybakb US Centers for Disease Control and Prevention (CDC) , National Center for Environmental Health , Atlanta , GA , USA.
Timothy D Phillipsd College of Veterinary Medicine and Biomedical Sciences , Texas A&M University , College Station , TX , USA.
Joel M Montgomerya US Centers for Disease Control and Prevention (CDC), Kenya , Center for Global Health , Nairobi , Kenya.
Lauren S Lewisb US Centers for Disease Control and Prevention (CDC) , National Center for Environmental Health , Atlanta , GA , USA.
Centers for Disease Control and Prevention · USTexas A&M University · USCenters for Disease Control and Prevention · KEKenya Medical Research Institute · KEMinistry of Health · KENational Center for Environmental Health · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Acute aflatoxin exposure can cause death and disease (aflatoxicosis) in humans. Aflatoxicosis fatality rates have been documented to be as high as 40% in Kenya. The inclusion in the diet of calcium silicate 100 (ACCS100), a calcium montmorillonite clay, may reduce aflatoxin bioavailability, thus potentially decreasing the risk of aflatoxicosis. We investigated the efficacy, acceptability and palatability of ACCS100 in a population in Kenya with recurring aflatoxicosis outbreaks. Healthy adult participants were enrolled in this double-blinded, crossover clinical trial in 2014. Following informed consent, participants (n = 50) were randomised to receive either ACCS100 (3 g day

Indexed as

DietEnvironmental ExposureAflatoxin B1BentoniteCross-Over StudiesFemaleHumansKenyaMaleAflatoxin B1BentoniteACCS100aflatoxicosisaflatoxincalcium montmorilloniteclayKenyaNovasiluniform particle size Novasil (UPSN)

Identifiers

PMID27603954
PMCPMC5561728
OpenAlexW2511652906

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.