Observational studyMedicine2016
New-onset ventricular arrhythmias post radiofrequency catheter ablation for atrial fibrillation.
Observational study in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- [Late complications after atrial fibrillation ablation : Diagnosis and management].Herzschrittmachertherapie & Elektrophysiologie · 2026Review
- Impact of catheter ablation for atrial fibrillation on cardiac ventricular electrical activity: assessment of premature ventricular complex burden.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Cardioneural ablation: Toward achieving uniformity in nomenclature, procedural approaches, and outcome measures.Heart rhythm · 2026Review
- Pulmonary vein isolation in a real-world population does not influence QTc interval.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2021Article
- Ventricular Tachycardia Storm After Standard Radiofrequency Pulmonary Vein Isolation.The American journal of case reports · 2019Article
- Ventricular Tachycardia (VT) Storm After Cryoballoon-Based Pulmonary Vein Isolation.The American journal of case reports · 2018Article
- Disruption of cardiac cholinergic neurons enhances susceptibility to ventricular arrhythmias.Nature communications · 2017Observational
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As a new complication, new-onset ventricular arrhythmias (VAs) post atrial fibrillation (AF) ablation have not been well defined. This prospective study aimed to describe the details of new-onset VAs post AF ablation in a large study cohort.One thousand fifty-three consecutive patients who underwent the first radiofrequency catheter ablation for AF were enrolled. All patients had no evidence of pre-ablation VAs. New-onset VAs were defined as new-onset ventricular tachycardia (VT) or premature ventricular contractions (PVC) ≥1000/24 h within 1 month post ablation.There were 46 patients (4.4%) who had 62 different new-onset VAs, among whom 42 were PVC alone, and 4 were PVC coexisting with nonsustained VT. Multivariate analysis showed that increased serum leukocyte counts ≥50% post ablation were independently associated with new-onset VAs (OR: 1.9; 95% CI: 1.0-3.5; P = 0.043). The median number of PVC was 3161 (1001-27,407) times/24 h. Outflow tract VAs were recorded in 35 (76.1%) patients. No significant differences were found in origin of VAs (P = 0.187). VAs disappeared without any treatment in 6 patients (13.0%). No VAs-related adverse cardiac event occurred.The study revealed a noticeable prevalence but relatively benign prognosis of new-onset VAs post AF ablation. Increased serum leukocyte counts ≥50% post ablation appeared to be associated with new-onset VAs, implying that inflammatory response caused by ablation might be the mechanism.
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Registered trials
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