ArticlePloS one2016
Sodium Disturbances in Children Admitted to a Kenyan Hospital: Magnitude, Outcome and Associated Factors.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 6 citations in OpenAlex.
- Low Blood Glucose and Its Relation to Electrolyte Derangements and Metabolic Acidosis in Critically Ill Children in Malawi.The American journal of tropical medicine and hygiene · 2026Article
- Hyponatremia and its associated factors in children admitted to the pediatric intensive care unit in eastern Ethiopia: a cross-sectional study.BMC pediatrics · 2023Article
- Prevalence and Clinical Significance of Hyponatremia in Pediatric Intensive Care.Journal of pediatric intensive care · 2019Article
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3 authors at 2 institutions in 2 countries.
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Abstract
backgroundPerturbations of blood sodium are the most frequently encountered electrolyte disorder in sick children, and may influence fluid therapy. We examined the frequency of blood sodium perturbations, and factors and outcomes associated with hyponatremia in children admitted to a rural Kenyan hospital and investigated the risk factors associated with deaths in hyponatremic children.
methodsPlasma sodium levels and other laboratory parameters were measured in children admitted to a rural Kenyan hospital. Clinical measurements were collected using standard forms and entered into a computer database. The proportion of children admitted with hyponatremia was determined. Logistic regression models were used to investigate factors associated with hyponatremia, and death in those with hyponatremia.
resultsAbnormal plasma sodium occurred in 46.6% (95% confidence interval (95%CI) 43.5-49.6%) of 1026 pediatric admissions. Hyponatremia occurred in 44.4% (95%CI 41.4-47.5%) and hypernatremia in 2.1% (95%CI 1.3-3.0%). Malaria (40.8%) was the most common underlying primary diagnosis in hyponatremic children. Malaria, hyperglycemia, wasting, high creatinine levels and preserved consciousness were associated with hyponatremia. Pallor and seizures were associated with increased mortality in hyponatremic children.
conclusionsSodium disturbances are common in pediatric admissions to a County hospital in rural Kenya. Seizures and pallor were predictors of mortality in hyponatremic children.
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