Evidence map›Paper›PMID 27603163›Full record

Trial reportAIDS (London, England)2016

A randomized, placebo-controlled pilot trial of N-acetylcysteine on oxidative stress and endothelial function in HIV-infected older adults receiving antiretroviral treatment.

Samir K Gupta, Lisa M Kamendulis, Matthias A Clauss, Ziyue Liu

Open access · greenAbstract readLetterRandomized Controlled Trial
In one paragraph

Trial report in AIDS (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Samir K GuptaaDivision of Infectious Diseases, Indiana University School of Medicine bDepartment of Environmental Health, Indiana University cDepartment of Cellular & Integrative Physiology, Center for Vascular Biology, Indiana University School of Medicine dDepartment of Biostatistics, Indiana University School of Medicine and School of Public Health, Indianapolis, Indiana, USA.
Lisa M Kamendulis
Matthias A Clauss
Ziyue Liu
Apple (Israel) · ILIndiana University School of Medicine

Funding

Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
EXTRAMURAL RESEARCH FACILITIES IMPROVEMENT: NEUROLOGICAL DISORDERS:ALZ, PDC06RR020128 · NCRR · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI FIFE, ROSE S · 2004 to 2004
$3.7M
NCATS NIH HHS UL1 TR001108NCRR NIH HHS C06 RR020128
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AcetylcysteineAgedAntiviral AgentsDouble-Blind MethodDrug Administration ScheduleEndothelium, VascularF2-IsoprostanesFree Radical ScavengersHIV InfectionsHumansMalondialdehydeMiddle AgedOxidative StressPilot ProjectsProspective StudiesAcetylcysteineAntiviral AgentsF2-IsoprostanesFree Radical ScavengersMalondialdehyde

Identifiers

PMID27603163
PMCPMC5015649
OpenAlexW2510446322

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.