Evidence map›Paper›PMID 27602308›Full record

ArticleIEEE journal of translational engineering in health and medicine2016

Point-of-Care Technologies for the Advancement of Precision Medicine in Heart, Lung, Blood, and Sleep Disorders.

Mary Emma Gorham Bigelow, Brian G Jamieson, Chi On Chui, Yufei Mao, Kyeong-Sik Shin, Tony Jun Huang, Po-Hsun Huang, Liqiang Ren, Bishow Adhikari, Jue Chen and 1 more

Open access · goldAbstract read
In one paragraph

Article in IEEE journal of translational engineering in health and medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Noninvasive wearable electroactive pharmaceutical monitoring for personalized therapeutics.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  3. Article
  4. Article
  5. Collaborative Paradigm of Preventive, Personalized, and Precision Medicine With Point-of-Care Technologies.IEEE journal of translational engineering in health and medicine · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Mary Emma Gorham BigelowDiagnostic Biochips, Inc. Glen Burnie MD 21051 USA.
Brian G JamiesonDiagnostic Biochips, Inc. Glen Burnie MD 21051 USA.
Chi On ChuiElectrical Engineering and Bioengineering Departments University of California at Los Angeles Los Angeles CA 90095 USA.
Yufei MaoElectrical Engineering and Bioengineering Departments University of California at Los Angeles Los Angeles CA 90095 USA.
Kyeong-Sik ShinElectrical Engineering and Bioengineering Departments University of California at Los Angeles Los Angeles CA 90095 USA.
Tony Jun HuangBioengineering Science and Mechanics Department The Pennsylvania State University University Park PA 16802 USA.
Po-Hsun HuangBioengineering Science and Mechanics Department The Pennsylvania State University University Park PA 16802 USA.
Liqiang RenBioengineering Science and Mechanics Department The Pennsylvania State University University Park PA 16802 USA.
Bishow AdhikariNational Heart, Lung, and Blood Institute Bethesda MD 20892 USA.
Jue ChenNational Heart, Lung, and Blood Institute Bethesda MD 20892 USA.
Erin IturriagaNational Heart, Lung, and Blood Institute Bethesda MD 20892 USA.
National Heart Lung and Blood Institute · USPennsylvania State University · USUniversity of California, Los Angeles · USDiagnostic Biochips (United States) · US

Funding

Semiconductor Electronic Label-Free Assay (SELFA) for Diagnosing Heart DiseaseR44HL123909 · NHLBI · SELFA, INC. · PI SHIN, KYEONG-SIK · 2014 to 2016
$1.7M
Indwelling Biosensor for real-time chemotherapeutic blood level monitoringR44HL126473 · NHLBI · DIAGNOSTIC BIOCHIPS, INC. · PI JAMIESON, BRIAN GLENN · 2016 to 2017
$1.3M
An Acoustofluidic Device for Point-of-Care Sputum Processing and AnalysisR43HL126441 · NHLBI · ASCENT BIO-NANO TECHNOLOGIES, INC. · PI WANG, LIN · 2015 to 2015
$225k
Indwelling biosensor for real-time chemotherapeutic blood level monitoringR43HL126473 · NHLBI · DIAGNOSTIC BIOCHIPS, INC. · PI JAMIESON, BRIAN GLENN · 2015 to 2015
$222k
NHLBI NIH HHS R43 HL126441NHLBI NIH HHS R43 HL126473NHLBI NIH HHS R44 HL123909NHLBI NIH HHS R44 HL126473
6 · The paper itself

Abstract

The commercialization of new point of care technologies holds great potential in facilitating and advancing precision medicine in heart, lung, blood, and sleep (HLBS) disorders. The delivery of individually tailored health care to a patient depends on how well that patient's health condition can be interrogated and monitored. Point of care technologies may enable access to rapid and cost-effective interrogation of a patient's health condition in near real time. Currently, physiological data are largely limited to single-time-point collection at the hospital or clinic, whereas critical information on some conditions must be collected in the home, when symptoms occur, or at regular intervals over time. A variety of HLBS disorders are highly dependent on transient variables, such as patient activity level, environment, time of day, and so on. Consequently, the National Heart Lung and Blood Institute sponsored a request for applications to support the development and commercialization of novel point-of-care technologies through small businesses (RFA-HL-14-011 and RFA-HL-14-017). Three of the supported research projects are described to highlight particular point-of-care needs for HLBS disorders and the breadth of emerging technologies. While significant obstacles remain to the commercialization of such technologies, these advancements will be required to achieve precision medicine.

Indexed as

Biosensorcommercializationpoint-of-care technologiesprecision medicine

Identifiers

PMID27602308
PMCPMC5003165
OpenAlexW2504748749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.