Evidence map›Paper›PMID 27602144›Full record

ArticleOncology letters2016

Possible intrinsic association of anti-neutrophil cytoplasmic antibody-associated vasculitis coexisting with multiple myeloma.

Huifang Liu, Jiachuan Xiong, Jun Zhang, Ying Zhang, Ling Nie, Yiqin Wang, Jinghong Zhao

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Huifang LiuDepartment of Nephrology, Institute of Nephrology of Chongqing and Kidney Center of the People's Liberation Army, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, P.R. China.
Jiachuan XiongDepartment of Nephrology, Institute of Nephrology of Chongqing and Kidney Center of the People's Liberation Army, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, P.R. China.
Jun ZhangDepartment of Nephrology, Institute of Nephrology of Chongqing and Kidney Center of the People's Liberation Army, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, P.R. China.
Ying ZhangDepartment of Nephrology, Institute of Nephrology of Chongqing and Kidney Center of the People's Liberation Army, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, P.R. China.
Ling NieDepartment of Nephrology, Institute of Nephrology of Chongqing and Kidney Center of the People's Liberation Army, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, P.R. China.
Yiqin WangDepartment of Nephrology, Institute of Nephrology of Chongqing and Kidney Center of the People's Liberation Army, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, P.R. China.
Jinghong ZhaoDepartment of Nephrology, Institute of Nephrology of Chongqing and Kidney Center of the People's Liberation Army, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, P.R. China.
Xinqiao Hospital · CNArmy Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a life-threatening condition that causes renal failure. Multiple myeloma (MM) is a malignant proliferation of monoclonal plasma cells in the blood that can also cause renal failure. The two diseases have high morbidity and mortality rates in the elderly, with a poor prognosis. A 64-year-old female presented to Xinqiao Hospital (Chonqing, China) with fatigue and a poor appetite that had been apparent for 6 weeks. Laboratory tests revealed a serum creatinine level of 10.31 mg/dl, a cytoplasmic ANCA titer of 1:10, a positive result for myeloperoxidase and a serum globulin level of 3.96 g/dl. A renal biopsy revealed crescent glomerulonephritis, combined with the rapid progression of renal function. Based on these observations (ANCA titer, crescent glomerulonephritis and rapid progression of renal function) a diagnosis of AAV was established. MM was confirmed by serum immunofixation electrophoresis combined with bone marrow aspiration. The present study discusses what is, to the best of our knowledge, the first case of AAV coexisting with MM in order to highlight it as a clinical concern.

Indexed as

anti-neutrophil cytoplasmic antibodydialysismultiple myelomarenal biopsy

Identifiers

PMID27602144
PMCPMC4998525
OpenAlexW2468531205

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.