Evidence map›Paper›PMID 27601953›Full record

ReviewReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology

Radiotherapy for Graves' disease. The possible role of low-dose radiotherapy.

Meritxell Arenas, Sebastià Sabater, Pedro Lara Jiménez, Àngels Rovirosa, Albert Biete, Victoria Linares, Montse Belles, Julià Panés

Open access · diamondAbstract readReview
In one paragraph

Review in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review of the treatment of Graves' ophthalmopathy: The role of the new radiation techniques.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Meritxell ArenasRadiation Oncology Department, Hospital Universitari Sant Joan de Reus, Institut d'Investigacions Sanitàries Pere Virgili (IISPV), Universitat Rovira i Virgili (URV), Tarragona, Spain.
Sebastià SabaterRadiation Oncology Department, Complejo Hospitalario Universitario Albacete (CHUA), Spain.
Pedro Lara JiménezRadiation Oncology Department, Hospital Universitario Dr Negrín, Universidad Las Palmas de Gran Canaria (LPGC), Las Palmas de Gran Canaria, Spain.
Àngels RovirosaRadiation Oncology Department, Hospital Universitari Clínic de Barcelona, Spain.
Albert BieteRadiation Oncology Department, Hospital Universitari Clínic de Barcelona, Spain.
Victoria LinaresLaboratory of Toxicology and Environmental Health, School of Medicine, IISPV, URV, Reus, Spain.
Montse BellesLaboratory of Toxicology and Environmental Health, School of Medicine, IISPV, URV, Reus, Spain.
Julià PanésGastroenterology Department, Hospital Universitari Clínic de Barcelona, Spain.
Hospital Universitari de Vic · ESInstitut de Recerca Biomèdica Catalunya Sud · ESComplejo Hospitalario Universitario de Albacete · ESHospital Universitario de Gran Canaria Doctor Negrín · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunomodulatory effects of low-dose radiotherapy (LD-RT) have been used for the treatment of several benign diseases, including arthrodegenerative and inflammatory pathologies. Graves' disease is an autoimmune disease and radiotherapy (RT) is a therapeutic option for ocular complications. The dose recommended in the clinical practice is 20 Gy (2 Gy/day). We hypothesized that lower doses (<10 Gy total dose, <1 Gy/day) could results in higher efficacy if we achieved anti-inflammatory and immunomodulatory effects of LD-RT. We review current evidence on the effects of RT in the treatment of Graves' disease and the possible use of LD-RT treatment strategy.

Indexed as

Graves’ ophthalmopathyLow-dose radiotherapyRadiotherapy for benign disease

Identifiers

PMID27601953
PMCPMC5002018
OpenAlexW2289973181

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.