Evidence map›Paper›PMID 27601804›Full record

ArticleJournal of oral and maxillofacial pathology : JOMFP

Evaluation of natural killer cell (CD57) as a prognostic marker in oral squamous cell carcinoma: An immunohistochemistry study.

Rashmi Agarwal, Minal Chaudhary, Shruti Bohra, Shree Bajaj

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In one paragraph

Article in Journal of oral and maxillofacial pathology : JOMFP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  11. Evaluation of lymphocyte apoptosis in patients with oral cancer.Journal of applied oral science : revista FOB · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rashmi AgarwalDepartment of Oral and Maxillofacial Pathology, Dr. B. R. Ambedkar Institute of Dental Sciences and Hospital, Patna, Bihar, India.
Minal ChaudharyDepartment of Oral and Maxillofacial Pathology and Microbiology, Sharad Pawar Dental College, Wardha, Maharashtra, India.
Shruti BohraDepartment of Oral and Maxillofacial Pathology and Microbiology, Sharad Pawar Dental College, Wardha, Maharashtra, India.
Shree BajajDepartment of Oral and Maxillofacial Pathology and Microbiology, Sharad Pawar Dental College, Wardha, Maharashtra, India.
Manubhai Patel Dental College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesNatural killer (NK) cells are important effector lymphocytes. NK cells are considered to represent innate immune system. NK cells target and kill aberrant cells such as virally infected and tumorigenic cells. The purpose of this study was to assess the expression of CD57 in oral squamous cell carcinoma (OSCC) and to correlate the expression of CD57 with 3 years survival in patients with OSCC. MATERIALS AND

methodsAbout 100 histopathologically diagnosed cases of OSCC of various grades were divided into two groups, i.e., Group I (dead patients) and Group II (live patients) from the archives of Department of Oral Pathology and Microbiology. CD57 was detected in these tissues by immunohistochemistry.

resultThe results were analyzed using Spearman's correlation coefficient and students unpaired t-test. The mean CD57 labeling index in Group II was significantly higher than that found in Group I (P = 0.000). There was a significant correlation (P = 0.00) in the mean CD57 levels between Groups I and II and prognosis of patient.

conclusionCD57 could be a good prognostic marker for OSCC patients.

Indexed as

CD57natural killer celloral canceroral squamous cell carcinoma

Identifiers

PMID27601804
PMCPMC4989542
OpenAlexW2467752848

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.