Evidence map›Paper›PMID 27601516›Full record

ReviewThe American journal of tropical medicine and hygiene2016

Herd Protection from Drinking Water, Sanitation, and Hygiene Interventions.

James A Fuller, Joseph N S Eisenberg

Abstract readReview
In one paragraph

Review in The American journal of tropical medicine and hygiene, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Does Basic Sanitation Prevent Diarrhea? Contextualizing Recent Intervention Trials through a Historical Lens.International journal of environmental research and public health · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

James A FullerDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan.
Joseph N S EisenbergDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan. jnse@umich.edu.

Funding

Environment Change and Diarrheal Disease: A Natural ExperimentR01AI050038 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI EISENBERG, JOSEPH N. S. · 2003 to 2012
$6.1M
Modeling the Effects of the Environment on Enteric Pathogen DynamicsU01GM110712 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI EISENBERG, JOSEPH N. S. · 2014 to 2018
$3.0M
NIAID NIH HHS R01 AI050038NIGMS NIH HHS U01 GM110712
6 · The paper itself

Abstract

Herd immunity arises when a communicable disease is less able to propagate because a substantial portion of the population is immune. Nonimmunizing interventions, such as insecticide-treated bednets and deworming drugs, have shown similar herd-protective effects. Less is known about the herd protection from drinking water, sanitation, and hand hygiene (WASH) interventions. We first constructed a transmission model to illustrate mechanisms through which different WASH interventions may provide herd protection. We then conducted an extensive review of the literature to assess the validity of the model results and identify current gaps in research. The model suggests that herd protection accounts for a substantial portion of the total protection provided by WASH interventions. However, both the literature and the model suggest that sanitation interventions in particular are the most likely to provide herd protection, since they reduce environmental contamination. Many studies fail to account for these indirect effects and thus underestimate the total impact an intervention may have. Although cluster-randomized trials of WASH interventions have reported the total or overall efficacy of WASH interventions, they have not quantified the role of herd protection. Just as it does in immunization policy, understanding the role of herd protection from WASH interventions can help inform coverage targets and strategies that indirectly protect those that are unable to be reached by WASH campaigns. Toward this end, studies are needed to confirm the differential role that herd protection plays across the WASH interventions suggested by our transmission model.

Indexed as

Communicable Disease ControlDrinking WaterEmpirical ResearchHand HygieneHumansHygieneModels, TheoreticalReproducibility of ResultsSanitationWater SupplyDrinking Water

Identifiers

PMID27601516
PMCPMC5094239

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.