Evidence map›Paper›PMID 27601253›Full record

ArticleJournal of physiology and biochemistry2016

Myo-inositol inhibits intestinal glucose absorption and promotes muscle glucose uptake: a dual approach study.

Chika Ifeanyi Chukwuma, Mohammed Auwal Ibrahim, Md Shahidul Islam

Abstract read
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In one paragraph

Article in Journal of physiology and biochemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 50 citations in OpenAlex.

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  15. Inositols in PCOS.Molecules (Basel, Switzerland) · 2020
    Review
  16. Review
  17. Review
  18. Inositols and metabolic disorders: From farm to bedside.Journal of traditional and complementary medicine · 2020
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Chika Ifeanyi ChukwumaDepartment of Biochemistry, School of Life Sciences, University of KwaZulu-Natal (Westville Campus), Durban, 4000, South Africa.
Mohammed Auwal IbrahimDepartment of Biochemistry, School of Life Sciences, University of KwaZulu-Natal (Westville Campus), Durban, 4000, South Africa.
Md Shahidul IslamDepartment of Biochemistry, School of Life Sciences, University of KwaZulu-Natal (Westville Campus), Durban, 4000, South Africa. islamd@ukzn.ac.za.
University of KwaZulu-Natal · ZAAhmadu Bello University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study investigated the effects of myo-inositol on muscle glucose uptake and intestinal glucose absorption ex vivo as well as in normal and type 2 diabetes model of rats. In ex vivo study, both intestinal glucose absorption and muscle glucose uptake were studied in isolated rat jejunum and psoas muscle respectively in the presence of increasing concentrations (2.5 % to 20 %) of myo-inositol. In the in vivo study, the effect of a single bolus dose (1 g/kg bw) of oral myo-inositol on intestinal glucose absorption, blood glucose, gastric emptying and digesta transit was investigated in normal and type 2 diabetic rats after 1 h of co-administration with 2 g/kg bw glucose, when phenol red was used as a recovery marker. Myo-inositol inhibited intestinal glucose absorption (IC

Indexed as

Administration, OralAnimalsBiological TransportBlood GlucoseCarbohydrate MetabolismDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2Dietary SupplementsDose-Response Relationship, DrugHyperglycemiaHypoglycemic AgentsInositolInsulinIntestinal AbsorptionJejunumMaleBlood GlucoseHypoglycemic AgentsInositolInsulinStreptozocinIntestinal glucose absorptionMuscle glucose uptakeMyo-inositolRatsType 2 diabetes

Identifiers

PMID27601253
OpenAlexW2507346113

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.