ReviewCurrent allergy and asthma reports2016
House Dust Mite Allergens: New Discoveries and Relevance to the Allergic Patient.
Review in Current allergy and asthma reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Efficacy of house dust mite allergen immunotherapy in allergic rhinitis: a network meta-analysis based on component-resolved classification.Frontiers in immunology · 2026Pooled it
- Enzyme-Crosslinked House Dust Mite Exhibits Reduced Allergenic Activity by Reprogramming the AMPKα-RALDH2 Axis in Type 1 Dendritic Cells.Clinical reviews in allergy & immunology · 2026Review
- Comparative clinical efficacy and immunological modulation of subcutaneous vs. sublingual allergen immunotherapy in children with house dust mite-induced allergic asthma: a retrospective cohort study.Frontiers in medicine · 2026Article
- Early Changes in House Dust Mite Component Specific Immunoglobulin Levels Predict the One-Year Efficacy of Allergen Immunotherapy in Patients With Allergic Rhinitis.Clinical and translational allergy · 2025Article
- Improved quality control of allergen products: Assessing the molecular allergen composition by mass spectrometry.Allergy · 2024Article
- An international seroprevalence survey of the IgE sensitisation to the Dermatophagoides farinae house dust mite and two of its major allergens (Der f 2, Zen 1) in atopic dogs.Veterinary dermatology · 2022Article
- Early life exposure to house dust mite allergen prevents experimental allergic asthma requiring mitochondrial HMucosal immunology · 2022Article
- Der p 1 Disrupts the Epithelial Barrier and Induces IL-6 Production in Patients With House Dust Mite Allergic Rhinitis.Frontiers in allergy · 2021Article
- IgE Epitopes of the House Dust Mite Allergen Der p 7 Are Mainly Discontinuous and Conformational.Frontiers in immunology · 2021Article
- Blimp-1 is essential for allergen-induced asthma and Th2 cell development in the lung.The Journal of experimental medicine · 2020Article
- Bedroom Allergen Exposure Beyond House Dust Mites.Current allergy and asthma reports · 2018Review
- Article
- Epidemiology of spider mite sensitivity: a meta-analysis and systematic review.Clinical and translational allergy · 2018Review
- Article
- Allergens with Protease Activity from House Dust Mites.International journal of molecular sciences · 2017Review
- Proteases of Dermatophagoides pteronyssinus.International journal of molecular sciences · 2017Article
- Natural Evolution of IgE Responses to Mite Allergens and Relationship to Progression of Allergic Disease: a Review.Current allergy and asthma reports · 2017Review
- Review
- A combined transcriptome and proteome analysis extends the allergome of house dust mite Dermatophagoides species.PloS one · 2017Article
- Allergen homologs in the Euroglyphus maynei draft genome.PloS one · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewRecent findings on house dust allergens and their contribution to knowledge that will significantly impact on current and future allergy treatments are appraised. RECENT
findingsQuantitation of IgE binding to a spectrum of allergen components in several independent studies in varying locations has largely affirmed the main components as the groups 1 and 2 and possibly 23 allergens with mid-tier contributions from the groups 4, 5, 7, and 21. Prevalent binding to Der p 23 has been recapitulated sometimes with low titers. The IgE of non-asthmatic atopic subjects binds at lower titer and to fewer components than that of asthmatics, and their IgG binding relative to IgE is higher especially for children hospitalized for exacerbation. The higher IgG ratios were associated with increased IL-10 a cytokine more readily induced from T cells of allergic subjects. Peptides representing the groups 1 and 2 allergens can be used to stimulate ex vivo T cells showing responses correlating with IgE binding and providing a valuable tool for ascertaining the contribution of IgE and T cells to disease. Also, the induction of Th2 and follicular helper T cells are shown to make different contributions in mice. Cross-reactivity of IgE binding assays with high-titer cross-reactive antibodies induced by scabies is a problem in the many areas of the world where scabies is highly prevalent and endemic and from recent increases in immigration. In the last few years, allergen research has produced results that warrant rapid translation into diagnostic tools and the formulation of allergen components for immunotherapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.