Evidence map›Paper›PMID 27600344›Full record

ArticleMicroarrays (Basel, Switzerland)2014

A New Modified Histogram Matching Normalization for Time Series Microarray Analysis.

Laura Astola, Jaap Molenaar

Abstract read
In one paragraph

Article in Microarrays (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The MKK3 MAPK cascade integrates temperature and after-ripening signals to modulate seed germination.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Laura AstolaDepartment of Biomedical Engineering, Eindhoven University of Technology, Eindhoven 5612 AZ,The Netherlands. l.j.astola@tue.nl.
Jaap MolenaarBiometris, Wageningen University and Research Centre, Wageningen 6708 PB, The Netherlands. jaap.molenaar@wur.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microarray data is often utilized in inferring regulatory networks. Quantile normalization (QN) is a popular method to reduce array-to-array variation. We show that in the context of time series measurements QN may not be the best choice for this task, especially not if the inference is based on continuous time ODE model. We propose an alternative normalization method that is better suited for network inference from time series data.

Indexed as

histogram matchingquantile normalizationtime series

Identifiers

PMID27600344
PMCPMC4996360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.