ReviewMicroarrays (Basel, Switzerland)2014
Overview on Techniques to Construct Tissue Arrays with Special Emphasis on Tissue Microarrays.
Review in Microarrays (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- An easy and reproducible method for rapid tissue macroarray block construction.Virchows Archiv : an international journal of pathology · 2025Article
- Correlation between Periostin Expression and Pro-Angiogenic Factors in Non-Small-Cell Lung Carcinoma.Cells · 2024Article
- Reinterpretation of prostate cancer pathology by Appl1, Sortilin and Syndecan-1 biomarkers.Scientific data · 2024Article
- TMA-Mate: An open-source modular toolkit for constructing tissue microarrays of arbitrary layouts.HardwareX · 2023Article
- Quality Assurance and Cost Reduction in Histopathology Laboratories Using Tissue Microarrays.Veterinary sciences · 2023Article
- A Simplified Method of Manually Constructing Small Format Tissue Microarray for Use in Resource-Constrained Settings.Iranian journal of pathology · 2023Article
- Comparative analysis of GOLPH3 expression in lymph node-positive prostate cancer: immunohistochemistry staining patterns and clinical significance.Frontiers in oncology · 2023Article
- Manual Construction of a Tissue Microarray using the Tape Method and a Handheld Microarrayer.Journal of visualized experiments : JoVE · 2022Article
- Recommendations for Tissue Microarray Construction and Quality Assurance.Applied immunohistochemistry & molecular morphology : AIMM · 2020Article
- An innovative diagnostic strategy for the detection of rare molecular targets to select cancer patients for tumor-agnostic treatments.Oncotarget · 2019Article
- Optimization of Tissue Microarrays from Banked Human Formalin-Fixed Paraffin Embedded Tissues in the Cancer Research Setting.Biopreservation and biobanking · 2019Article
- Autophagy is positively associated with the accumulation of myeloid‑derived suppressor cells in 4‑nitroquinoline‑1‑oxide‑induced oral cancer.Oncology reports · 2018Article
- Living Cell Microarrays: An Overview of Concepts.Microarrays (Basel, Switzerland) · 2016Review
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Authors and funding
1 author.
Funding
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Abstract
With the advent of new histopathological staining techniques (histochemistry, immunohistochemistry, in situ hybridization) and the discovery of thousands of new genes, mRNA, and proteins by molecular biology, the need grew for a technique to compare many different cells or tissues on one slide in a cost effective manner and with the possibility to easily track the identity of each specimen: the tissue array (TA). Basically, a TA consists of at least two different specimens per slide. TAs differ in the kind of specimens, the number of specimens installed, the dimension of the specimens, the arrangement of the specimens, the embedding medium, the technique to prepare the specimens to be installed, and the technique to construct the TA itself. A TA can be constructed by arranging the tissue specimens in a mold and subsequently pouring the mold with the embedding medium of choice. In contrast, preformed so-called recipient blocks consisting of the embedding medium of choice have punched, drilled, or poured holes of different diameters and distances in which the cells or tissue biopsies will be deployed manually, semi-automatically, or automatically. The costs of constructing a TA differ from a few to thousands of Euros depending on the technique/equipment used. Remarkably high quality TAs can be also achieved by low cost techniques.
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