Evidence map›Paper›PMID 27600267›Full record

ArticleEpigenomics2016

miRNA-140-5p: new avenue for pulmonary arterial hypertension drug development?

Alexander Mk Rothman, David J Rowlands, Allan Lawrie

Abstract readEditorialComment
PubMed Publisher
In one paragraph

Article in Epigenomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. The pharmaco-epigenetics of hypertension: a focus on microRNA.Molecular and cellular biochemistry · 2024
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Alexander Mk RothmanDepartment of Infection, Immunity & Cardiovascular Disease, University of Sheffield, Sheffield, S10 2RX, UK.
David J RowlandsNovartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
Allan LawrieDepartment of Infection, Immunity & Cardiovascular Disease, University of Sheffield, Sheffield, S10 2RX, UK.

Funding

British Heart Foundation FS/13/48/30453British Heart Foundation PG/11/116/29288Medical Research Council G0800318Medical Research Council MR/K002406/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hypertension, PulmonaryMicroRNAsHumansMicroRNAsmiR140-5pmiRNApulmonary arterial hypertensionremodelingSmurf1ubiquitination

Identifiers

PMID27600267

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.