ArticleSkeletal radiology2016
Intraosseous hibernoma: a rare adipocytic bone tumour.
Article in Skeletal radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Test yourself answer: 38-year-old female with left hip pain.Skeletal radiology · 2026Article
- Intraosseous hibernoma mimicking sclerotic bone metastasis-a case report.Skeletal radiology · 2025Article
- Intraosseous Hibernoma: A Rare Entity in Orthopedics With Peculiar Radiological Features.Cureus · 2023Article
- Benign incidental do-not-touch bone lesions.The British journal of radiology · 2023Review
- Intraosseous hibernoma: Two case reports and a review of the literature.Radiology case reports · 2022Article
- Intraosseous hibernoma of the appendicular skeleton.Skeletal radiology · 2022Article
- Diagnosis of Intraosseous Hibernoma of an Appendicular Skeleton in an Adult - A Rare Case Report.Journal of orthopaedic case reports · 2022Article
- Immunophenotypic expression of UCP1 in hibernoma and other adipose/non adipose soft tissue tumours.Clinical sarcoma research · 2019Article
- Pleomorphic liposarcoma of bone: a rare primary malignant bone tumour.Clinical sarcoma research · 2018Article
- Oxidative stress-induced S100B accumulation converts myoblasts into brown adipocytes via an NF-κB/YY1/miR-133 axis and NF-κB/YY1/BMP-7 axis.Cell death and differentiation · 2017Article
- Intraosseous Hibernoma: A Rare and Unique Intraosseous Lesion.Journal of pathology and translational medicine · 2017Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hibernoma is a benign adipose tumour that contains foetal brown fat cells. We report a case of hibernoma arising in the left ischium of a 65-year-old female with a past history of ovarian carcinoma. The patient presented with a relatively short history of left sacral/hip pain. Radiologically, the lesion, which was large (5 cm) and sclerotic, had been stable for a number of years. Histologically, it was composed mainly of plump cells with foamy, multivacuolated cytoplasm. These cells showed no reaction for epithelial, melanoma or leucocyte markers but expressed FABP4/aP2 and S100, indicating that they were brown fat cells. There was no mitotic activity or nuclear pleomorphism and the lesion was diagnosed as a benign intraosseous hibernoma (IOH). IOH is a recently identified benign adipocytic lesion that presents typically as a sclerotic bone lesion. It has characteristic morphological and immunophenotypic features and should be regarded as a discrete primary bone tumour that needs to be distinguished from metastatic carcinoma/melanoma, chondrosarcoma and metabolic storage diseases containing numerous foamy macrophages.
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