Evidence map›Paper›PMID 27600066›Full record

ArticleDiabetes2016

Zinc-Associated Variant in SLC30A8 Gene Interacts With Gestational Weight Gain on Postpartum Glycemic Changes: A Longitudinal Study in Women With Prior Gestational Diabetes Mellitus.

Tiange Wang, Huikun Liu, Leishen Wang, Tao Huang, Weiqin Li, Yan Zheng, Yoriko Heianza, Dianjianyi Sun, Junhong Leng, Shuang Zhang and 3 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Association ofFrontiers in endocrinology · 2023
    Pooled it
  2. Article
  3. Review
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Tiange WangDepartment of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA.
Huikun LiuTianjin Women and Children's Health Center, Tianjin, China.
Leishen WangTianjin Women and Children's Health Center, Tianjin, China.
Tao HuangEpidemiology Domain, Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Weiqin LiTianjin Women and Children's Health Center, Tianjin, China.
Yan ZhengDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.
Yoriko HeianzaDepartment of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA.
Dianjianyi SunDepartment of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA.
Junhong LengTianjin Women and Children's Health Center, Tianjin, China.
Shuang ZhangTianjin Women and Children's Health Center, Tianjin, China.
Nan LiTianjin Women and Children's Health Center, Tianjin, China.
Gang HuPennington Biomedical Research Center, Baton Rouge, LA.
Lu QiDepartment of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA lqi1@tulane.edu luqi@hsph.harvard.edu.
Tianjin Children's Hospital · CNTulane University · USHarvard University · USNational University Health System · SGPennington Biomedical Research Center · USShanghai Institute of Hematology · CN

Funding

Transgenic CoreP30DK046200 · NIDDK · TUFTS MEDICAL CENTER · PI GREENBERG, ANDREW S, PERISSI, VALENTINA · 1992 to 2021
$25.0M
RISK FACTORS FOR CVD IN WOMENR01HL034594 · NHLBI · TULANE UNIVERSITY OF LOUISIANA · PI JoAnn Elisabeth Manson, Lu Qi · 1985 to 2026
$13.8M
Common Genetic Variation and Quantitative Diabetes TraitsR01DK078616 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI MEIGS, JAMES B · 2008 to 2014
$5.0M
Genetic Markers of CHD in Type 2 DiabetesR01HL071981 · NHLBI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI QI, LU · 2003 to 2012
$4.9M
Obesity Genes, Energy Regulation in Response to Weight-Loss DietsR01DK091718 · NIDDK · TULANE UNIVERSITY OF LOUISIANA · PI QI, LU · 2012 to 2021
$4.5M
Weight-Loss Diet Intervention on Cardiometabolic Factors of Gut MicrobiotaR01DK100383 · NIDDK · TULANE UNIVERSITY OF LOUISIANA · PI QI, LU · 2014 to 2024
$4.2M
TOPMed Omics of Type 2 Diabetes and Quantitative TraitsUM1DK078616 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI MANNING, ALISA KNODLE · 2021 to 2025
$3.8M
Rare Sequence Variation and Diabetes Quantitative TraitsU01DK078616 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI MEIGS, JAMES B · 2015 to 2019
$3.6M
Methylomics of prenatal GDM: Natural history & lifestyle intervention in childrenR01DK100790 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI BACCARELLI, ANDREA, HOU, LIFANG · 2014 to 2017
$2.6M
Genome-wide interactions with diet patterns on long-term weight changeR21HL126024 · NHLBI · TULANE UNIVERSITY OF LOUISIANA · PI QI, LU · 2015 to 2016
$421k
NHLBI NIH HHS R01 HL034594NHLBI NIH HHS R01 HL071981NHLBI NIH HHS R21 HL126024NIDDK NIH HHS P30 DK046200NIDDK NIH HHS R01 DK078616NIDDK NIH HHS R01 DK091718NIDDK NIH HHS R01 DK100383NIDDK NIH HHS R01 DK100790NIDDK NIH HHS U01 DK078616NIDDK NIH HHS UM1 DK078616
6 · The paper itself

Abstract

Zinc transporter 8 genetic variant SLC30A8 has been associated with postpartum risk of type 2 diabetes among women with gestational diabetes mellitus (GDM). Gestational weight gain is one of the strongest risk factors for postpartum hyperglycemia. We assessed the interaction between type 2 diabetes-associated SLC30A8 rs13266634 and gestational weight gain on 1-5 years of postpartum glycemic changes in 1,071 women with prior GDM in a longitudinal study. Compared with gestation of 26-30 weeks, postpartum levels of fasting glucose, oral glucose tolerance test 2-h glucose, and hemoglobin A

Indexed as

AdultBlood GlucoseCation Transport ProteinsDiabetes, GestationalFemaleGenotypeGestational AgeGlucose Tolerance TestGlycated HemoglobinHumansHyperglycemiaLongitudinal StudiesPostpartum PeriodPregnancyRetrospective StudiesRisk FactorsBlood GlucoseCation Transport ProteinsGlycated HemoglobinSLC30A8 protein, humanZincZinc Transporter 8

Identifiers

PMID27600066
PMCPMC5127244
OpenAlexW2513889968

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.