Evidence map›Paper›PMID 27600036›Full record

ArticleAntimicrobial agents and chemotherapy2016

Ceftriaxone-Resistant Neisseria gonorrhoeae Isolates (2010 to 2014) in France Characterized by Using Whole-Genome Sequencing.

Claire de Curraize, Sylvain Kumanski, Maïté Micaëlo, Nelly Fournet, Guy La Ruche, Fabienne Meunier, Rishma Amarsy, Hervé Jacquier, Emmanuelle Cambau, Agathe Goubard and 1 more

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Emergence and evolution of mosaicFrontiers in microbiology · 2024
    Article
  3. Review
  4. Review
  5. Antimicrobial susceptibility ofEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2020
    Observational
  6. Review
  7. Pharmacokinetic Data Are Predictive ofAntimicrobial agents and chemotherapy · 2019
    Article
  8. Review
  9. Antimicrobial resistance and molecular epidemiology using whole-genome sequencing of Neisseria gonorrhoeae in Ireland, 2014-2016: focus on extended-spectrum cephalosporins and azithromycin.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018
    Article
  10. Persistence of an outbreak of gonorrhoea with high-level resistance to azithromycin in England, November 2014‒May 2018.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2018
    Article
  11. Article
  12. Multidrug-resistantEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2018
    Article
  13. Article
  14. Article
  15. Drug-resistant Neisseria gonorrhoeae: latest developments.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017
    Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Claire de CurraizeLaboratory of Bacteriology, University Hospital of Dijon, Dijon, France.
Sylvain KumanskiAPHP, Lariboisière-St Louis-Fernand Widal Hospital, Laboratory of Bacteriology, Associated Laboratory for the National Reference Centre for Gonococci, Paris, France.
Maïté MicaëloAPHP, Lariboisière-St Louis-Fernand Widal Hospital, Laboratory of Bacteriology, Associated Laboratory for the National Reference Centre for Gonococci, Paris, France.
Nelly FournetFrench Institute for Public Heath Surveillance (InVS), Department of Infectious Diseases, Saint-Maurice, France.
Guy La RucheFrench Institute for Public Heath Surveillance (InVS), Department of Infectious Diseases, Saint-Maurice, France.
Fabienne MeunierAPHP, Lariboisière-St Louis-Fernand Widal Hospital, Laboratory of Bacteriology, Associated Laboratory for the National Reference Centre for Gonococci, Paris, France.
Rishma AmarsyAPHP, Lariboisière-St Louis-Fernand Widal Hospital, Laboratory of Bacteriology, Associated Laboratory for the National Reference Centre for Gonococci, Paris, France.
Hervé JacquierAPHP, Lariboisière-St Louis-Fernand Widal Hospital, Laboratory of Bacteriology, Associated Laboratory for the National Reference Centre for Gonococci, Paris, France.
Emmanuelle CambauAPHP, Lariboisière-St Louis-Fernand Widal Hospital, Laboratory of Bacteriology, Associated Laboratory for the National Reference Centre for Gonococci, Paris, France.
Agathe GoubardAlfred Fournier Institute, National Reference Centre for Gonococci, Paris, France.
Béatrice BercotAPHP, Lariboisière-St Louis-Fernand Widal Hospital, Laboratory of Bacteriology, Associated Laboratory for the National Reference Centre for Gonococci, Paris, France beatrice.bercot@aphp.fr.ORCID 0000-0003-1603-3635

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two extended-spectrum cephalosporin-resistant Neisseria gonorrhoeae isolates were discovered among 6,340 (0.03%) French isolates between 2010 and 2014. One isolate corresponded to the F89 multidrug-resistant N. gonorrhoeae isolate harboring a penA mosaic; whole-genome sequencing highlighted an additional R251H substitution in the ftsX gene recently involved in cephalosporin resistance. The other, ceftriaxone-resistant isolate (MIC, 0.25 mg/liter) harbored the PBP2 pattern XXXVI plus a P551S substitution and belonged to sequence type ST1579 (multilocus sequence typing [MLST]).

Indexed as

Anti-Bacterial AgentsBacterial ProteinsCefiximeCeftriaxoneCell Cycle ProteinsCephalosporin ResistanceFranceGenome, BacterialHumansMicrobial Sensitivity TestsMultilocus Sequence TypingMutationNeisseria gonorrhoeaeAnti-Bacterial AgentsBacterial ProteinsCefiximeCeftriaxoneCell Cycle ProteinsFtsX protein, bacteria

Identifiers

PMID27600036
PMCPMC5075118

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.