ReviewAdvanced drug delivery reviews2017
The use of hyperpolarized carbon-13 magnetic resonance for molecular imaging.
Review in Advanced drug delivery reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- [Research Progress in Applying HyperpolarizedSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024Review
- Quantification of Prostate Cancer Metabolism Using 3D Multiecho bSSFP and Hyperpolarized [1-Journal of magnetic resonance imaging : JMRI · 2023Article
- Molecular MRI-Based Monitoring of Cancer Immunotherapy Treatment Response.International journal of molecular sciences · 2023Review
- Imaging drug delivery to the lungs: Methods and applications in oncology.Advanced drug delivery reviews · 2023Review
- Multinuclear MRI in Drug Discovery.Molecules (Basel, Switzerland) · 2022Review
- Simple Esterification of [1-ACS chemical biology · 2021Article
- Robust detection of oncometabolic aberrations byCommunications biology · 2020Article
- HyperpolarizedJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020Review
- Metabolic Imaging and Biological Assessment: Platforms to Evaluate Acute Lung Injury and Inflammation.Frontiers in physiology · 2020Review
- Probing carbohydrate metabolism using hyperpolarizedNMR in biomedicine · 2019Review
- Imaging the Injured Lung: Mechanisms of Action and Clinical Use.Anesthesiology · 2019Review
- The beginning of the end for conventional RECIST - novel therapies require novel imaging approaches.Nature reviews. Clinical oncology · 2019Review
- Review Article: Synthesis, properties, and applications of fluorescent diamond particles.Journal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B · 2019Review
- HyperpolarizedNeoplasia (New York, N.Y.) · 2019Review
- Identification of Intracellular and Extracellular Metabolites in Cancer Cells UsingAnalytical chemistry · 2018Article
- Evaluation of Active Brown Adipose Tissue by the Use of Hyperpolarized [1-International journal of molecular sciences · 2018Article
- Hyperpolarized carbon-13 magnetic resonance spectroscopic imaging: a clinical tool for studying tumour metabolism.The British journal of radiology · 2018Review
- Lung Metabolism and Inflammation during Mechanical Ventilation; An Imaging Approach.Scientific reports · 2018Article
- Aqueous, Heterogeneous Parahydrogen-InducedThe journal of physical chemistry. C, Nanomaterials and interfaces · 2017Article
- Magnetic resonance imaging with hyperpolarized agents: methods and applications.Physics in medicine and biology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Until recently, molecular imaging using magnetic resonance (MR) has been limited by the modality's low sensitivity, especially with non-proton nuclei. The advent of hyperpolarized (HP) MR overcomes this limitation by substantially enhancing the signal of certain biologically important probes through a process known as external nuclear polarization, enabling real-time assessment of tissue function and metabolism. The metabolic information obtained by HP MR imaging holds significant promise in the clinic, where it could play a critical role in disease diagnosis and therapeutic monitoring. This review will provide a comprehensive overview of the developments made in the field of hyperpolarized MR, including advancements in polarization techniques and delivery, probe development, pulse sequence optimization, characterization of healthy and diseased tissues, and the steps made towards clinical translation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.