ArticleScientific reports2016
Continuous and selective measurement of oxytocin and vasopressin using boron-doped diamond electrodes.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 49 citations in OpenAlex.
- Neural vs Neuromorphic Interfaces: Where Are We Standing?Chemical reviews · 2025Review
- The Oxytocin System and Implications for Oxytocin Deficiency in Hypothalamic-Pituitary Disease.Endocrine reviews · 2025Review
- An Internally Attached Aptameric Graphene Nanosensor for Sensitive Vasopressin Measurement in Critical Patient Monitoring.ACS sensors · 2024Article
- Near-infrared nanosensors enable optical imaging of oxytocin with selectivity over vasopressin in acute mouse brain slices.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Highly Specific Detection of Oxytocin in Saliva.International journal of molecular sciences · 2023Article
- Advances on Hormones and Steroids Determination: A Review of Voltammetric Methods since 2000.Membranes · 2022Review
- Probing Neuropeptide Volume Transmission In Vivo by Simultaneous Near-Infrared Light-Triggered Release and Optical Sensing.Angewandte Chemie (International ed. in English) · 2022Article
- Optimized Sawhorse Waveform for the Measurement of Oxytocin Release in Zebrafish.Analytical chemistry · 2022Article
- Investigation of the structure-activity relationship in a series of new LVV- and VV-hemorphin-7 analogues designed as potential anticonvulsant agents.Amino acids · 2022Article
- Current and future techniques for detecting oxytocin: Focusing on genetically-encoded GPCR sensors.Journal of neuroscience methods · 2022Review
- Noninvasive wearable electroactive pharmaceutical monitoring for personalized therapeutics.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Latest Trends in Electrochemical Sensors for Neurotransmitters: A Review.Sensors (Basel, Switzerland) · 2019Review
- Boron Doped Diamond Electrodes in Flow-Based Systems.Frontiers in chemistry · 2019Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The electrochemical detection of oxytocin using boron-doped diamond (BDD) electrodes was studied. Cyclic voltammetry of oxytocin in a phosphate buffer solution exhibits an oxidation peak at +0.7 V (vs. Ag/AgCl), which is attributable to oxidation of the phenolic group in the tyrosyl moiety. Furthermore, the linearity of the current peaks obtained in flow injection analysis (FIA) using BDD microelectrodes over the oxytocin concentration range from 0.1 to 10.0 μM with a detection limit of 50 nM (S/N = 3) was high (R(2) = 0.995). Although the voltammograms of oxytocin and vasopressin observed with an as-deposited BDD electrode, as well as with a cathodically-reduced BDD electrode, were similar, a clear distinction was observed with anodically-oxidized BDD electrodes due to the attractive interaction between vasopressin and the oxidized BDD surface. By means of this distinction, selective measurements using chronoamperometry combined with flow injection analysis at an optimized potential were demonstrated, indicating the possibility of making selective in situ or in vivo measurements of oxytocin.
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