Evidence map›Paper›PMID 27599784›Full record

ArticleAIDS research and human retroviruses2017

Soluble Factors Secreted by Endothelial Cells Allow for Productive and Latent HIV-1 Infection in Resting CD4

John Henry Morris, Tran Nguyen, Abuoma Nwadike, Mackenzie L Geels, Derrick L Kamp, Bo Ram Kim, Jean D Boyer, Anding Shen

Open access · bronzeAbstract read
In one paragraph

Article in AIDS research and human retroviruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Endothelial Cells Promote Productive HIV Infection of Resting CD4AIDS research and human retroviruses · 2022
    Article
  3. The reservoir of latent HIV.Frontiers in cellular and infection microbiology · 2022
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

John Henry Morris1 Department of Biology, Calvin College , Grand Rapids, Michigan.
Tran Nguyen1 Department of Biology, Calvin College , Grand Rapids, Michigan.
Abuoma Nwadike1 Department of Biology, Calvin College , Grand Rapids, Michigan.
Mackenzie L Geels1 Department of Biology, Calvin College , Grand Rapids, Michigan.
Derrick L Kamp1 Department of Biology, Calvin College , Grand Rapids, Michigan.
Bo Ram Kim1 Department of Biology, Calvin College , Grand Rapids, Michigan.
Jean D Boyer2 Department of Pathology and Laboratory Medicine, University of Pennsylvania , Philadelphia, Pennsylvania.
Anding Shen1 Department of Biology, Calvin College , Grand Rapids, Michigan.
Calvin University · USUniversity of Pennsylvania · US

Funding

Roles of endothelial cells in HIV infection and latency in resting CD4+ T cellsR15AI096991 · NIAID · CALVIN UNIVERSITY · PI SHEN, ANDING · 2011 to 2020
$975k
NIAID NIH HHS R15 AI096991
6 · The paper itself

Abstract

In vitro, it is difficult to infect resting CD4

Indexed as

Cell CommunicationVirus LatencyCD4-Positive T-LymphocytesCytokinesEndothelial CellsHIV-1HumansCytokinesHIVHIV/AIDS pathogenesisT cellsviral reservoirs

Identifiers

PMID27599784
PMCPMC5312546
OpenAlexW2512749206

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.