ArticleNature communications2016
DNA transposon activity is associated with increased mutation rates in genes of rice and other grasses.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 57 citations in OpenAlex.
- Transposable elements as evolutionary catalysts of ant macrodiversity.Science advances · 2026Article
- Chromosome-Level Genome Assembly of the Loach Goby Rhyacichthys aspro Offers Insights Into Gobioidei Evolution.Molecular ecology resources · 2025Article
- Retrotransposon-driven environmental regulation of FLC leads to adaptive response to herbicide.Nature plants · 2024Article
- Microbiome and plant cell transformation trigger insect gall induction in cassava.Frontiers in plant science · 2023Article
- Structure characteristics of mutation sites in two waxy alleles from Yunnan waxy maize (Zea mays L. var. certaina Kulesh) landraces.PloS one · 2023Article
- Transposable elements maintain genome-wide heterozygosity in inbred populations.Nature communications · 2022Article
- High Nucleotide Substitution Rates Associated with Retrotransposon Proliferation Drive Dynamic Secretome Evolution in Smut Pathogens.Microbiology spectrum · 2022Article
- Identification and Characterization ofGenes · 2022Article
- IntraspecificNAR genomics and bioinformatics · 2022Article
- Review
- Ancient Gene Duplications, Rather Than Polyploidization, Facilitate Diversification of Petal Pigmentation Patterns in Clarkia gracilis (Onagraceae).Molecular biology and evolution · 2021Article
- Adult resistance genes to barley powdery mildew confer basal penetration resistance associated with broad-spectrum resistance.The plant genome · 2021Article
- Article
- The genomic ecosystem of transposable elements in maize.PLoS genetics · 2021Article
- Long-read sequence assembly: a technical evaluation in barley.The Plant cell · 2021Article
- Genetic and environmental modulation of transposition shapes the evolutionary potential of Arabidopsis thaliana.Genome biology · 2021Article
- CicerSpTEdb: A web-based database for high-resolution genome-wide identification of transposable elements in Cicer species.PloS one · 2021Article
- Functional regulation of an ancestral RAG transposon ProtoRAG by a trans-acting factor YY1 in lancelet.Nature communications · 2020Article
- TRITEX: chromosome-scale sequence assembly of Triticeae genomes with open-source tools.Genome biology · 2019Article
- Parallelism and convergence in post-domestication adaptation in cereal grasses.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Review
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Authors and funding
11 authors at 6 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DNA (class 2) transposons are mobile genetic elements which move within their 'host' genome through excising and re-inserting elsewhere. Although the rice genome contains tens of thousands of such elements, their actual role in evolution is still unclear. Analysing over 650 transposon polymorphisms in the rice species Oryza sativa and Oryza glaberrima, we find that DNA repair following transposon excisions is associated with an increased number of mutations in the sequences neighbouring the transposon. Indeed, the 3,000 bp flanking the excised transposons can contain over 10 times more mutations than the genome-wide average. Since DNA transposons preferably insert near genes, this is correlated with increases in mutation rates in coding sequences and regulatory regions. Most importantly, we find this phenomenon also in maize, wheat and barley. Thus, these findings suggest that DNA transposon activity is a major evolutionary force in grasses which provide the basis of most food consumed by humankind.
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