ReviewInternational journal of molecular medicine2016
The molecular basis of fertilization (Review).
Review in International journal of molecular medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 105 citations in OpenAlex.
- The Role of Sperm Proteins IZUMO1 and TMEM95 in Mammalian Fertilization: A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Development of placental abnormalities in location and anatomy.Acta obstetricia et gynecologica Scandinavica · 2020Pooled it
- Sperm mitochondrial sheath formation - how and why?Nature reviews. Urology · 2026Review
- Couple-level dyslipidemia and embryological and cumulative pregnancy outcomes in IVF/ICSI cycles: a single-center retrospective cohort study.Frontiers in endocrinology · 2026Article
- Role of Seminal Exosomes in Reproduction.Journal of cellular physiology · 2025Review
- POU4F2/Brn-3b is Essential for Spermatogenesis and its Disruption is Linked to Male Infertility in Mice and Humans.Research square · 2025Article
- Influence of Cryopreservation on the Acrosome Reaction in Hucul Stallion Spermatozoa.Animals : an open access journal from MDPI · 2025Article
- IMPACT OF REAL-LIFE ENVIRONMENTAL EXPOSURES ON REPRODUCTION: Phthalates disrupt female reproductive health: a call for enhanced investigation into mixtures.Reproduction (Cambridge, England) · 2025Review
- Plant-based bioactives and oxidative stress in reproduction: anti-inflammatory and metabolic protection mechanisms.Frontiers in nutrition · 2025Review
- Cell fusion dynamics: mechanisms of multinucleation in osteoclasts and macrophages.Inflammation and regeneration · 2024Review
- Overview of the expression patterns and roles of Lipocalin 2 in the reproductive system.Frontiers in endocrinology · 2024Review
- Ferulic acid ameliorates the quality ofAging · 2023Article
- Exposure to Cumulus Cell Secretome Improves Sperm Function: New Perspectives for Sperm Selection In Vitro.Cells · 2023Article
- Exploration of the preterm birth risk-related heat event thresholds for pregnant women: a population-based cohort study in China.The Lancet regional health. Western Pacific · 2023Article
- Review
- A novel heterozygous variant in PANX1 causes primary infertility due to oocyte death.Journal of assisted reproduction and genetics · 2023Article
- Intercellular communication in the cumulus-oocyte complex during folliculogenesis: A review.Frontiers in cell and developmental biology · 2023Review
- Sperm Chromatin Condensation Defect Accelerates the Kinetics of Early Embryonic Development but Does Not Modify ICSI Outcome.International journal of molecular sciences · 2022Article
- Unravelling the genetics of non-random fertilization associated with gametic incompatibility.Scientific reports · 2022Article
- Role of extracellular vesicles in intercellular communication during reproduction.Reproduction in domestic animals = Zuchthygiene · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fertilization is the fusion of the male and female gamete. The process involves the fusion of an oocyte with a sperm, creating a single diploid cell, the zygote, from which a new individual organism will develop. The elucidation of the molecular mechanisms of fertilization has fascinated researchers for many years. In this review, we focus on this intriguing process at the molecular level. Several molecules have been identified to play a key role in each step of this intriguing process (the sperm attraction from the oocyte, the sperm maturation, the sperm and oocyte fusion and the two gamete pronuclei fusion leading to the zygote). Understanding the molecular mechanisms of the cell‑cell interactions will provide a better understanding of the causes of fertility issues due to fertilization defects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.