Evidence map›Paper›PMID 27599518›Full record

ArticleDoklady. Biochemistry and biophysics2016

Methylglyoxal as a scavenger for superoxide anion-radical.

K B Shumaev, V Z Lankin, G G Konovalova, M A Grechnikova, A K Tikhaze

Abstract read
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In one paragraph

Article in Doklady. Biochemistry and biophysics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

K B ShumaevBach Institute of Biochemistry, Federal Research Center "Fundamentals of Biotechnology,", Russian Academy of Sciences, Leninskii pr. 33, Moscow, 119071, Russia. gavakon5050@mail.ru.
V Z LankinRussian Cardiology Research and Production Association, Ministry of Public Health of the Russian Federation, 3-ya Cherepkovskaya ul. 15a, Moscow, 121552, Russia.
G G KonovalovaRussian Cardiology Research and Production Association, Ministry of Public Health of the Russian Federation, 3-ya Cherepkovskaya ul. 15a, Moscow, 121552, Russia.
M A GrechnikovaRussian Cardiology Research and Production Association, Ministry of Public Health of the Russian Federation, 3-ya Cherepkovskaya ul. 15a, Moscow, 121552, Russia.
A K TikhazeRussian Cardiology Research and Production Association, Ministry of Public Health of the Russian Federation, 3-ya Cherepkovskaya ul. 15a, Moscow, 121552, Russia.
Institute of Experimental Cardiology · RURussian Academy of Sciences · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methylglyoxal at a concentration of 5 mM caused a significant inhibition of superoxide anion radical (O2 (·-)) comparable to the effect of Tirone. In the process of O2 (·-) generation in the system of egg phosphatidylcholine liposome peroxidation induced by the azo-initiator AIBN, a marked inhibition of chemiluminescence in the presence of 100 mM methylglyoxal was found. At the same time, methylglyoxal did not inhibit free radical peroxidation of low-density lipoprotein particles, which indicates the absence of interaction with methylglyoxal alkoxyl and peroxyl polyenoic lipid radicals. These findings deepen information about the role of methylglyoxal in the regulation of free radical processes.

Indexed as

Egg ProteinsFree Radical ScavengersLipid PeroxidationLipoproteins, LDLLiposomesLuminescent MeasurementsModels, ChemicalNitrilesPhosphatidylcholinesPyruvaldehydeSuperoxidesazobis(isobutyronitrile)Egg ProteinsFree Radical ScavengersLipoproteins, LDLLiposomesNitrilesPhosphatidylcholinesPyruvaldehydeSuperoxides

Identifiers

PMID27599518
OpenAlexW2519373635

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.