Evidence map›Paper›PMID 27599499›Full record

ReviewMolecular neurobiology2017

GABAergic Regulation of Adult Hippocampal Neurogenesis.

Mirjam Sibbe, Akos Kulik

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 80 citations in OpenAlex.

  1. Trial
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  4. Review
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  11. Review
  12. The role of GABA in modulation of taste signaling within the taste bud.Pflugers Archiv : European journal of physiology · 2024
    Article
  13. Article
  14. Adult neurogenesis: a real hope or a delusion?Neural regeneration research · 2024
    Review
  15. Article
  16. Function of the GABAergic System in Diabetic Encephalopathy.Cellular and molecular neurobiology · 2023
    Review
  17. Multisession Anodal Transcranial Direct Current Stimulation Enhances Adult Hippocampal Neurogenesis and Context Discrimination in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mirjam SibbeCentre for Neuroscience, Institute of Anatomy and Cell Biology, University of Freiburg, Albertstr. 23, 79104, Freiburg, Germany. Mirjam.Sibbe@gmx.de.
Akos KulikInstitute of Physiology, University of Freiburg, Hermann-Herder-Str. 7, 79104, Freiburg, Germany.
University of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adult hippocampal neurogenesis has been implicated in several brain functions, including learning and memory processes. It also plays an important role in the aetiology of anxiety disorders, depression and age-related deficits. The endogenous stem cell pool is also known to hold great potential for ameliorating the diseased or aged brain. It has been shown that certain brain activities lead to an adjustment of adult neurogenesis, which can further be controlled by the interplay between inhibitory and excitatory processes. The roles of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) in the proliferation and differentiation of stem cells and progenitor cells, as well as in the control of network activity of hippocampal stem cells, have been extensively investigated in recent decades. This review highlights the general functions of GABAergic signalling and provides an exciting insight into the diverse functions of GABA in adult hippocampal stem cell biology.

Indexed as

AnimalsCell Differentiationgamma-Aminobutyric AcidHippocampusHumansNeurogenesisNeuronsStem Cellsgamma-Aminobutyric AcidAdult neurogenesisGABAGABAARGABABRHippocampal stem cellHippocampusProliferationStem cell quiescence

Identifiers

PMID27599499
OpenAlexW2518264775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.