Evidence map›Paper›PMID 27599493›Full record

ArticleMolecular diversity2017

Efficient one-pot synthesis of new 1-amino substituted pyrrolo[1,2-a]quinoline-4-carboxylate esters via copper-free Sonogashira coupling reactions.

Ali Keivanloo, Shaghayegh Sadat Kazemi, Hossein Nasr-Isfahani, Abdolhamid Bamoniri

Abstract read
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In one paragraph

Article in Molecular diversity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ali KeivanlooSchool of Chemistry, Shahrood University of Technology, Shahrood, Iran. akeivanloo@yahoo.com.
Shaghayegh Sadat KazemiSchool of Chemistry, Shahrood University of Technology, Shahrood, Iran.
Hossein Nasr-IsfahaniSchool of Chemistry, Shahrood University of Technology, Shahrood, Iran.
Abdolhamid BamoniriChemistry Faculty, University of Kashan, Kashan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The reactions of several 2-chloroquinoline-3-carboxylate esters with propargyl alcohol and a secondary amine in the presence of palladium catalyst leads to the formation of new alkyl 1-amino substituted pyrrolo[1,2-a]quinoline-4-carboxylate derivatives. This one-pot process, carried out in the absence of any copper salt, provides an efficient method for the synthesis of functionalized pyrrolo[1,2-a]quinolines in good-to-high yields.

Indexed as

AlkynesCarboxylic AcidsCatalysisChemistry Techniques, SyntheticEstersQuinolinesAlkynesCarboxylic AcidsEstersQuinolinesCopper-freePalladium catalystPropargyl alcoholPyrrolo[1,2-a]quinolineSonogashira coupling

Identifiers

PMID27599493

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.