ArticleBMC genomics2016
Whole genome sequence analysis indicates recent diversification of mammal-associated Campylobacter fetus and implicates a genetic factor associated with H2S production.
Article in BMC genomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 31 citations in OpenAlex.
- Lineage-associated differences in adenine methylation patterns of mammalian-associatedMicrobiology spectrum · 2026Article
- Biochemical and molecular characterization of Campylobacter fetus isolates from bulls subjected to bovine genital campylobacteriosis diagnosis in Spain.BMC veterinary research · 2024Article
- Comparative pangenomic analysis of Campylobacter fetus isolated from Spanish bulls and other mammalian species.Scientific reports · 2024Article
- Whole-genome comparison using complete genomes fromFrontiers in microbiology · 2024Article
- Antimicrobial resistance inMicrobial genomics · 2023Article
- Molecular diagnosis of bovine genital campylobacteriosis using high-resolution melting analysis.Frontiers in microbiology · 2022Article
- Genomic epidemiology ofFrontiers in veterinary science · 2022Article
- Genomic and Phenotypic Characterization ofMicroorganisms · 2021Article
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- Pathogenomics of EmergingClinical microbiology reviews · 2019Review
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- Living in Cold Blood:Frontiers in microbiology · 2019Review
- Article
- Homologous Recombination between Genetically Divergent Campylobacter fetus Lineages Supports Host-Associated Speciation.Genome biology and evolution · 2018Article
- Diagnosis of Bovine Genital Campylobacteriosis in South America.Frontiers in veterinary science · 2018Review
- Distinct Campylobacter fetus lineages adapted as livestock pathogens and human pathobionts in the intestinal microbiota.Nature communications · 2017Article
- Genome Reduction for Niche Association inFrontiers in cellular and infection microbiology · 2017Article
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCampylobacter fetus (C. fetus) can cause disease in both humans and animals. C. fetus has been divided into three subspecies: C. fetus subsp. fetus (Cff), C. fetus subsp. venerealis (Cfv) and C. fetus subsp. testudinum (Cft). Subspecies identification of mammal-associated C. fetus strains is crucial in the control of Bovine Genital Campylobacteriosis (BGC), a syndrome associated with Cfv. The prescribed methods for subspecies identification of the Cff and Cfv isolates are: tolerance to 1 % glycine and H2S production.
resultsIn this study, we observed the deletion of a putative cysteine transporter in the Cfv strains, which are not able to produce H2S from L-cysteine. Phylogenetic reconstruction of the core genome single nucleotide polymorphisms (SNPs) within Cff and Cfv strains divided these strains into five different clades and showed that the Cfv clade and a Cff clade evolved from a single Cff ancestor.
conclusionsMultiple C. fetus clades were observed, which were not consistent with the biochemical differentiation of the strains. This suggests the need for a closer evaluation of the current C. fetus subspecies differentiation, considering that the phenotypic differentiation is still applied in BGC control programs.
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