Evidence map›Paper›PMID 27599331›Full record

ArticleJAMA2016

Screening for Latent Tuberculosis Infection in Adults: US Preventive Services Task Force Recommendation Statement.

US Preventive Services Task Force, Kirsten Bibbins-Domingo, David C Grossman, Susan J Curry, Linda Bauman, Karina W Davidson, John W Epling, Francisco A R García, Jessica Herzstein, Alex R Kemper and 7 more

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PubMed Publisher
In one paragraph

Article in JAMA, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed, 2 pooled it
15.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 2 syntheses or guidelines pooled it, 183 citations in OpenAlex.

  1. Pooled it
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  12. Latent TB treatment outcomes in patients with chronic liver disease: A retrospective cohort study.Journal of clinical tuberculosis and other mycobacterial diseases · 2025
    Article
  13. Article
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  15. Article
  16. Latent Tuberculosis Infection Testing Practices in a Large US Integrated Healthcare System.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  17. Article
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  19. Cost-effectiveness of expanded latent TB infection testing and treatment: Lynn City, Massachusetts, USA.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2024
    Article
  20. Article

55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 13 institutions in 1 country.

US Preventive Services Task Force
Kirsten Bibbins-DomingoUniversity of California, San Francisco.
David C GrossmanGroup Health Research Institute, Seattle, Washington.
Susan J CurryUniversity of Iowa, Iowa City.
Linda BaumanUniversity of Wisconsin-Madison.
Karina W DavidsonColumbia University, New York, New York.
John W EplingState University of New York Upstate Medical University, Syracuse.
Francisco A R GarcíaPima County Department of Health, Tucson, Arizona.
Jessica HerzsteinIndependent consultant, Washington, DC.
Alex R KemperDuke University, Durham, North Carolina.
Alex H KristFairfax Family Practice Residency, Fairfax, Virginia11Virginia Commonwealth University, Richmond.
Ann E KurthYale University, New Haven, Connecticut.
C Seth LandefeldUniversity of Alabama at Birmingham.
Carol M MangioneUniversity of California, Los Angeles.
William R PhillipsUniversity of Washington, Seattle.
Maureen G PhippsBrown University, Providence, Rhode Island.
Michael P PignoneUniversity of Texas at Austin.
Duke University · USSUNY Upstate Medical University · USUniversity of California, Los Angeles · USUniversity of Iowa · USBrown University · USIndependent Sector · USKaiser Permanente Washington Health Research Institute · USThe University of Texas at Austin · USUniversity of Alabama at Birmingham · USUniversity of California, San Francisco · USUniversity of Washington · USUniversity of Wisconsin–Madison · USVirginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importanceTuberculosis remains an important preventable disease in the United States. An effective strategy for reducing the transmission, morbidity, and mortality of active disease is the identification and treatment of latent tuberculosis infection (LTBI) to prevent progression to active disease.

objectiveTo issue a current US Preventive Services Task Force (USPSTF) recommendation on screening for LTBI. EVIDENCE REVIEW: The USPSTF reviewed the evidence on screening for LTBI in asymptomatic adults seen in primary care, including evidence dating from the inception of searched databases.

findingsThe USPSTF found adequate evidence that accurate screening tests for LTBI are available, treatment of LTBI provides a moderate health benefit in preventing progression to active disease, and the harms of screening and treatment are small. The USPSTF has moderate certainty that screening for LTBI in persons at increased risk for infection provides a moderate net benefit. CONCLUSIONS AND RECOMMENDATION: The USPSTF recommends screening for LTBI in populations at increased risk. (B recommendation).

Indexed as

Advisory CommitteesLatent TuberculosisAdultHumansMass ScreeningPrimary Health CareRisk AssessmentTuberculosis

Identifiers

PMID27599331
OpenAlexW2509460207

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.