Evidence map›Paper›PMID 27599152›Full record

ArticleFuture microbiology2016

Direct detection of Helicobacter pylori in biopsy specimens using a high-throughput multiple genetic detection system.

Yanmei Zhang, Shiwen Wang, Binjie Hu, Fuju Zhao, Ping Xiang, Danian Ji, Fei Chen, Xiaoli Liu, Feng Yang, Yong Wu and 9 more

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in Future microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Advances in Diagnostic Modalities forLife (Basel, Switzerland) · 2024
    Review
  2. Article
  3. Article
  4. DifferentialPathogens (Basel, Switzerland) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 2 countries.

Yanmei ZhangDepartment of Laboratory Medicine, Huadong Hospital affiliated to Fudan University, No. 221 Yanan West Road, Shanghai 200040, China.
Shiwen WangDepartment of Laboratory Medicine, Huadong Hospital affiliated to Fudan University, No. 221 Yanan West Road, Shanghai 200040, China.
Binjie HuDepartment of Laboratory Medicine, Huadong Hospital affiliated to Fudan University, No. 221 Yanan West Road, Shanghai 200040, China.
Fuju ZhaoDepartment of Laboratory Medicine, Huadong Hospital affiliated to Fudan University, No. 221 Yanan West Road, Shanghai 200040, China.
Ping XiangDepartment of Endoscopy, Huadong Hospital affiliated to Fudan University, No. 221 Yanan West Road, Shanghai 200040, China.
Danian JiDepartment of Endoscopy, Huadong Hospital affiliated to Fudan University, No. 221 Yanan West Road, Shanghai 200040, China.
Fei ChenDepartment of Laboratory Medicine, Huadong Hospital affiliated to Fudan University, No. 221 Yanan West Road, Shanghai 200040, China.
Xiaoli LiuCancer Institute, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Feng YangDepartment of Laboratory Medicine, Huadong Hospital affiliated to Fudan University, No. 221 Yanan West Road, Shanghai 200040, China.
Yong WuNingbo HEALTH Gene Technologies Co., Ltd, Ningbo 315000, PR China.
Mimi KongNingbo HEALTH Gene Technologies Co., Ltd, Ningbo 315000, PR China.
Li NanNingbo HEALTH Gene Technologies Co., Ltd, Ningbo 315000, PR China.
Yingxin MiaoDepartment of Laboratory Medicine, Huadong Hospital affiliated to Fudan University, No. 221 Yanan West Road, Shanghai 200040, China.
Wenrong JiangDepartment of Laboratory Medicine, Huadong Hospital affiliated to Fudan University, No. 221 Yanan West Road, Shanghai 200040, China.
Yi FangDepartment of Laboratory Medicine, Huadong Hospital affiliated to Fudan University, No. 221 Yanan West Road, Shanghai 200040, China.
Jinghao ZhangDepartment of Laboratory Medicine, Huadong Hospital affiliated to Fudan University, No. 221 Yanan West Road, Shanghai 200040, China.
Zhijun BaoDepartment of Gastroenterology, Gerontology Institute of Shanghai affiliated to Huadong Hospital affiliated to Fudan University, No. 221 Yanan West Road, Shanghai 200040, China.
Michal A OlszewskiDepartment of Internal Medicine, Division of Pulmonary & Critical Care Medicine, University of Michigan Medical School & Veterans' Affairs Ann Arbor Health System, Ann Arbor, MI 48105, USA.
Hu ZhaoDepartment of Laboratory Medicine, Huadong Hospital affiliated to Fudan University, No. 221 Yanan West Road, Shanghai 200040, China.
Huadong Hospital · CNFudan University · CNNingbo College of Health Sciences · CNYangPu Geriatric Hospital · CNFudan University Shanghai Cancer Center · CNVA Ann Arbor Healthcare System · US

Funding

Modulation of Pulmonary Defenses in Pathobiology of Chronic InfectionsI01BX000656 · VA · VETERANS HEALTH ADMINISTRATION · PI OLSZEWSKI, MICHAL A · 2011 to 2025
–
BLR&D Research Career Scientist Award ApplicationIK6BX003615 · VA · VETERANS HEALTH ADMINISTRATION · PI OLSZEWSKI, MICHAL A · 2017 to 2021
–
BLRD VA I01 BX000656BLRD VA IK6 BX003615
6 · The paper itself

Abstract

aimWe evaluated the direct high-throughput multiple genetic detection system (dHMGS) for Helicobacter pylori in gastric biopsies. MATERIALS &

methodsOne hundred and thirty-three specimens were concurrently analyzed by dHMGS, rapid urease test, culture and sequencing.

resultsdHMGS was highly sensitive and specific for H. pylori identification compared with culture and rapid urease test. The correlation coefficient of the quantitative standard curve was R

conclusionThe dHMGS could efficiently diagnose and quantify H. pylori burden in biopsies, simultaneously screening for virulence, antibiotic resistance and presence of the multistrain infections.

Indexed as

AdultAgedAged, 80 and overBacterial ProteinsBiopsyDNA, BacterialFemaleHelicobacter InfectionsHelicobacter pyloriHigh-Throughput Nucleotide SequencingHumansMaleMiddle AgedPolymerase Chain ReactionSensitivity and SpecificityUreaseBacterial ProteinsDNA, BacterialUreasedirect high-throughput multiple genetic detection systemgastric biopsy specimensHelicobacter pyloriidentificationmixed infectionquantitative analysisresistancevirulence

Identifiers

PMID27599152
PMCPMC5562010
OpenAlexW2511864302

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.