Evidence map›Paper›PMID 27598781›Full record

ArticleThe Angle orthodontist2017

Antimicrobial and physical characteristics of orthodontic primers containing antimicrobial agents.

Shin-Hye Chung, Soha Cho, Kyungsun Kim, Bum-Soon Lim, Sug-Joon Ahn

Open access · diamondAbstract read
In one paragraph

Article in The Angle orthodontist, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

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  12. Functional Coatings for Orthodontic Archwires-A Review.Materials (Basel, Switzerland) · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Shin-Hye Chung
Soha Cho
Kyungsun Kim
Bum-Soon Lim
Sug-Joon Ahn
Seoul National University Dental Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the antimicrobial and physical properties of experimental primers containing chlorhexidine (CHX) or ursolic acid (UA) with a commercial primer. MATERIALS AND

methodsTwo antibacterial agents, 3 mg each of CHX and UA were incorporated respectively into 1 ml of Transbond XT primer (TX) to form antibacterial primers, TX-CHX and TX-UA. The antimicrobial activity of the three primers (TX, TX-CHX, and TX-UA) against Streptococcus mutans in both planktonic and biofilm phases was analyzed by determining minimum inhibitory and bactericidal concentrations and by performing growth and biofilm assays. Growth and biofilm assays were performed in both the absence and presence of thermocycling in a water tank to analyze the effects of water aging on the antimicrobial activities of primers. After bonding brackets onto bovine incisors using the primers, shear bond strength and mode of fracture were analyzed to compare physical properties.

resultsTX-CHX had stronger antimicrobial activity against S. mutans in the planktonic and biofilm phases than did TX or TX-UA. When applied, TX-CHX completely inhibited the growth and biofilm formation of S. mutans . In addition, the antimicrobial activity of TX-CHX was maintained after thermocycling. However, TX-UA did not show significant antimicrobial activity compared with TX. There was no significant difference in either shear bond strength or bond failure interface among the primers.

conclusionIncorporation of CHX into an orthodontic primer may help prevent enamel demineralization around surfaces without compromising its physical properties.

Indexed as

Orthodontic BracketsAnimalsAnti-Infective AgentsBiofilmsCattleChlorhexidineDental BondingIn Vitro TechniquesMicrobial Sensitivity TestsResin CementsStreptococcus mutansSurface PropertiesTooth DemineralizationTriterpenesUrsolic AcidAnti-Infective AgentsChlorhexidineResin CementsTransbond XTTriterpenesUrsolic AcidAntimicrobialBondingBond strengthOrthodontic primer

Identifiers

PMID27598781
PMCPMC8384363
OpenAlexW2508482299

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.