ArticleToxins2016
Confirmation and Fine Mapping of a Major QTL for Aflatoxin Resistance in Maize Using a Combination of Linkage and Association Mapping.
Article in Toxins, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 30 citations in OpenAlex.
- The Effect ofPlants (Basel, Switzerland) · 2025Article
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- Genetic basis of maize maternal haploid induction beyondFrontiers in plant science · 2023Article
- Comprehensive meta-analysis of QTL and gene expression studies identify candidate genes associated withFrontiers in plant science · 2023Article
- Comprehensive evaluation of Chinese peanut mini-mini core collection and QTL mapping for aflatoxin resistance.BMC plant biology · 2022Article
- Comparative transcriptome profiling and co-expression network analysis uncover the key genes associated withearly-stage resistance to Aspergillus flavus in maize.BMC plant biology · 2021Article
- Breeding Maize Maternal Haploid Inducers.Plants (Basel, Switzerland) · 2020Review
- Genome-wide association study leads to novel genetic insights into resistance to Aspergillus flavus in maize kernels.BMC plant biology · 2020Article
- Use of Dual RNA-seq for Systems Biology Analysis ofFrontiers in microbiology · 2020Article
- Functional Biology and Molecular Mechanisms of Host-Pathogen Interactions for Aflatoxin Contamination in Groundnut (Frontiers in microbiology · 2020Review
- Genomics-assisted breeding for ear rot resistances and reduced mycotoxin contamination in maize: methods, advances and prospects.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2019Review
- Genetic determinants controlling maize rubisco activase gene expression and a comparison with rice counterparts.BMC plant biology · 2019Article
- Aflatoxin in maize: a review of the early literature from "moldy-corn toxicosis" to the genetics of aflatoxin accumulation resistance.Mycotoxin research · 2019Review
- Identification of candidate resistance genes of cotton againstPhysiology and molecular biology of plants : an international journal of functional plant biology · 2018Article
- Seed-Derived Ethylene Facilitates Colonization but Not Aflatoxin Production byFrontiers in plant science · 2017Article
- Comparative Histological and Transcriptional Analysis of Maize Kernels Infected withFrontiers in plant science · 2017Article
- Identification of Major Quantitative Trait Loci for Seed Oil Content in Soybeans by Combining Linkage and Genome-Wide Association Mapping.Frontiers in plant science · 2017Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maize grain contamination with aflatoxin from Aspergillus flavus (A. flavus) is a serious health hazard to animals and humans. To map the quantitative trait loci (QTLs) associated with resistance to A. flavus, we employed a powerful approach that differs from previous methods in one important way: it combines the advantages of the genome-wide association analysis (GWAS) and traditional linkage mapping analysis. Linkage mapping was performed using 228 recombinant inbred lines (RILs), and a highly significant QTL that affected aflatoxin accumulation, qAA8, was mapped. This QTL spanned approximately 7 centi-Morgan (cM) on chromosome 8. The confidence interval was too large for positional cloning of the causal gene. To refine this QTL, GWAS was performed with 558,629 single nucleotide polymorphisms (SNPs) in an association population comprising 437 maize inbred lines. Twenty-five significantly associated SNPs were identified, most of which co-localised with qAA8 and explained 6.7% to 26.8% of the phenotypic variation observed. Based on the rapid linkage disequilibrium (LD) and the high density of SNPs in the association population, qAA8 was further localised to a smaller genomic region of approximately 1500 bp. A high-resolution map of the qAA8 region will be useful towards a marker-assisted selection (MAS) of A. flavus resistance and a characterisation of the causal gene.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.