Evidence map›Paper›PMID 27598190›Full record

ArticleViruses2016

A Decrease in Temperature and Humidity Precedes Human Rhinovirus Infections in a Cold Climate.

Tiina M Ikäheimo, Kari Jaakkola, Jari Jokelainen, Annika Saukkoriipi, Merja Roivainen, Raija Juvonen, Olli Vainio, Jouni J K Jaakkola

Abstract read
In one paragraph

Article in Viruses, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. SARS-CoV-2 Survival on Surfaces. Measurements Optimisation for an Enthalpy-Based Assessment of the Risk.International journal of environmental research and public health · 2023
    Article
  3. Article
  4. Review
  5. Impact of Selected Meteorological Factors on COVID-19 Incidence in Southern Finland during 2020-2021.International journal of environmental research and public health · 2022
    Article
  6. Prevalence of Common Diseases in Indigenous People in Colombia.Tropical medicine and infectious disease · 2022
    Article
  7. Article
  8. Article
  9. Predicting SARS-CoV-2 Weather-Induced Seasonal Virulence from Atmospheric Air Enthalpy.International journal of environmental research and public health · 2020
    Article
  10. Article
  11. Article
  12. On the Optimal Indoor Air Conditions for SARS-CoV-2 Inactivation. An Enthalpy-Based Approach.International journal of environmental research and public health · 2020
    Article
  13. Article
  14. Environmental and Health Effects of Ventilation in Subway Stations: A Literature Review.International journal of environmental research and public health · 2020
    Review
  15. Article
  16. Biological fluid dynamics of airborne COVID-19 infection.Rendiconti Lincei. Scienze fisiche e naturali · 2020
    Review
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tiina M IkäheimoCenter for Environmental and Respiratory Health Research, University of Oulu, P.O. Box 5000, FI-90014 Oulu, Finland. tiina.ikaheimo@oulu.fi.
Kari JaakkolaCenter for Environmental and Respiratory Health Research, University of Oulu, P.O. Box 5000, FI-90014 Oulu, Finland. kari.jaakkola@mil.fi.
Jari JokelainenFaculty of Medicine, University of Oulu, P.O. Box 5000, FI-90014 Oulu, Finland. jari.jokelainen@oulu.fi.
Annika SaukkoriipiImpact Assessment Unit, Department of Health Protection, National Institute for Health and Welfare, P.O. Box 310, FI-90101 Oulu, Finland. annika.saukkoriipi@thl.fi.
Merja RoivainenViral Infections Unit, Department of Infectious Disease, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland. merja.roivainen@outlook.com.
Raija JuvonenDepartment of Otorhinolaryngology Kainuu Central Hospital, Sotkamontie 13, FI-87140 Kajaani, Finland. raija.juvonen@kainuu.fi.
Olli VainioMedical Research Center, University of Oulu and Oulu University Hospital, FI-90014 Oulu, Finland. olli.vainio@oulu.fi.
Jouni J K JaakkolaCenter for Environmental and Respiratory Health Research, University of Oulu, P.O. Box 5000, FI-90014 Oulu, Finland. jouni.jaakkola@oulu.fi.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both temperature and humidity may independently or jointly contribute to the risk of human rhinovirus (HRV) infections, either through altered survival and spread of viruses in the environment or due to changes in host susceptibility. This study examined the relationship between short-term variations in temperature and humidity and the risk of HRV infections in a subarctic climate. We conducted a case-crossover study among conscripts (n = 892) seeking medical attention due to respiratory symptoms during their military training and identified 147 HRV cases by real-time PCR. An average temperature, a decline in daily ambient temperature and absolute humidity (AH) during the three preceding days of the onset (hazard period) and two reference periods (a week prior and after the onset) were obtained. The average daily temperature preceding HRV infections was -9.9 ± 4.9 °C and the average AH was 2.2 ± 0.9 g/m³. An average (odds ratios (OR) 1.07 (95% confidence interval (CI) 1.00-1.15)) and maximal (OR 1.08 (1.01-1.17)) change in temperature increased the risk of HRV infections by 8% per 1 °C decrease. An average (OR 1.20 (CI 1.03-1.40)) and maximal decrease (OR 1.13 (CI 0.96-1.34)) in AH increased the risk of HRV infection by 13% and 20% per 0.5 g/m³ decrease. A higher average temperature during the three preceding days was positively associated with HRV infections (OR 1.07 (CI 1.00-1.15)). A decrease rather than low temperature and humidity per se during the preceding few days increases the risk of HRV infections in a cold climate. The information is applicable to populations residing in cold climates for appropriate personal protection and prevention of adverse health effects.

Indexed as

Cold TemperatureEnvironmental ExposureHumidityCold ClimateCommon ColdCross-Over StudiesHumansMaleMilitary PersonnelPolymerase Chain ReactionRhinovirusYoung Adultabsolute humidityhuman rhinoviruslow temperature

Identifiers

PMID27598190
PMCPMC5035958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.