Evidence map›Paper›PMID 27598162›Full record

ArticleSensors (Basel, Switzerland)2016

A Disposable Microfluidic Device with a Screen Printed Electrode for Mimicking Phase II Metabolism.

Rafaela Vasiliadou, Mohammad Mehdi Nasr Esfahani, Nathan J Brown, Kevin J Welham

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rafaela VasiliadouDepartment of Chemistry, University of Hull, Cottingham Road, Hull HU6 7RX, UK. R.Vasiliadou@hull.ac.uk.
Mohammad Mehdi Nasr EsfahaniDepartment of Engineering, University of Hull, Cottingham Road, Hull HU6 7RX, UK. m.m.n.esfahani@gmail.com.
Nathan J BrownDepartment of Engineering, University of Hull, Cottingham Road, Hull HU6 7RX, UK. N.J.Brown@hull.ac.uk.
Kevin J WelhamDepartment of Chemistry, University of Hull, Cottingham Road, Hull HU6 7RX, UK. k.j.welham@hull.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human metabolism is investigated using several in vitro methods. However, the current methodologies are often expensive, tedious and complicated. Over the last decade, the combination of electrochemistry (EC) with mass spectrometry (MS) has a simpler and a cheaper alternative to mimic the human metabolism. This paper describes the development of a disposable microfluidic device with a screen-printed electrode (SPE) for monitoring phase II GSH reactions. The proposed chip has the potential to be used as a primary screening tool, thus complementing the current in vitro methods.

Indexed as

MetabolismDihydroxyphenylalanineElectrochemistryElectrodesElectrolysisGlutathioneMass SpectrometryMicrofluidicsDihydroxyphenylalanineGlutathioneelectrochemistrymass spectrometrymetabolismscreen-printed electrodes

Identifiers

PMID27598162
PMCPMC5038696

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.