ArticleInternational journal of molecular sciences2016
Pereskia aculeata Muller (Cactaceae) Leaves: Chemical Composition and Biological Activities.
Article in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Antibacterial Activity of Corryocactus brevistylus (Sanky) Methanolic Extract Against Staphylococcus aureus and Enterococcus faecalis.BioMed research international · 2026Article
- Unveiling the Phytochemical Diversity ofPharmaceuticals (Basel, Switzerland) · 2025Article
- Selective Extraction Process and Characterization of Antioxidant Phenolic Compounds fromACS omega · 2024Article
- A Critical Appraisal of the Most Recent Investigations on Ora-Pro-Nobis (Plants (Basel, Switzerland) · 2023Review
- Elaboration and Characterization ofMetabolites · 2023Article
- Encapsulation and dispersion of Lactobacillus acidophilus in a chocolate coating as a strategy for maintaining cell viability in cereal bars.Scientific reports · 2021Article
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Authors and funding
6 authors.
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Abstract
The aims of this work were to study the chemical composition of the essential oil from the leaves of Pereskia aculeata and to evaluate some biological activities of three leaf extracts. The phenolic content, antioxidant activity, and in vitro antimicrobial and antifungal activities were determined. The methanol extract showed antioxidant activity (EC50 7.09 mg/mL) and high polyphenols content (15.04 ± 0.31 mg gallic acid equivalents (GAE)/g). The petroleum ether extract exhibited potent antibacterial activity against Escherichia coli, whereas the chloroform extract showed inhibitory activity against Bacillus cereus and Staphylococcus aureus. The petroleum ether and methanol extracts were more effective in inhibiting the growth of Aspergillus versicolor. The possible cytotoxicity of extracts on neuroblastoma SH-SY5Y cancer cell line and the influence on adenylate cyclase (ADCY) expression was also studied. P. aculeata chloroform extract showed antiproliferative activity with an IC50 value of 262.83 µg/mL. Treatments of SH-SY5Y neuroblastoma cells with 100 µg/mL of methanol extract significantly reduced ADCY1 expression.
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