ArticleJournal of the American Chemical Society2016
The Mechanism of N-N Double Bond Cleavage by an Iron(II) Hydride Complex.
Article in Journal of the American Chemical Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 47 citations in OpenAlex.
- Iron-Catalyzed Tunable Double Bond Migration and Geometrical Isomerization in Olefins via a Spin-Accelerated Alkyl Mechanism.Angewandte Chemie (International ed. in English) · 2025Article
- Facile N═N Bond Cleavage of Cis-Azobenzene with Bis-silylenes.Angewandte Chemie (International ed. in English) · 2025Article
- Lewis Base-Enhanced C-H Bond Functionalization Mediated by a Diiron Imido Complex.Inorganic chemistry · 2025Article
- Low-Coordinate Iron Hydride Chemistry at an N,N,C-Heteroscorpionate Platform.Inorganic chemistry · 2024Article
- Terminal Hydride Complex of High-Spin Mn.Journal of the American Chemical Society · 2024Article
- Mössbauer and Nuclear Resonance Vibrational Spectroscopy Studies of Iron Species Involved in N-N Bond Cleavage.Inorganic chemistry · 2023Article
- Mechanism of Nitrogen Reduction to Ammonia in a Diiron Model of Nitrogenase.Inorganic chemistry · 2023Article
- Recent Advances to Mediate Reductive Processes of Nitroarenes Using Single-Electron Transfer, Organomagnesium, or Organozinc Reagents.Synthesis · 2022Article
- N═N Bond Cleavage by Tantalum Hydride Complexes: Mechanistic Insights and Reactivity.Inorganic chemistry · 2022Article
- Synthesis of Chromium(II) Complexes with Chelating Bis(alkoxide) Ligand and Their Reactions with Organoazides and Diazoalkanes.Molecules (Basel, Switzerland) · 2020Article
- A model for dinitrogen binding in the EChemical science · 2019Article
- Computational Approach to Molecular Catalysis by 3d Transition Metals: Challenges and Opportunities.Chemical reviews · 2019Article
- An S =Journal of the American Chemical Society · 2018Article
- A Thermodynamic Model for Redox-Dependent Binding of Carbon Monoxide at Site-Differentiated, High Spin Iron Clusters.Journal of the American Chemical Society · 2018Article
- Nitrogen Reduction to Ammonia on a Biomimetic Mononuclear Iron Centre: Insights into the Nitrogenase Enzyme.Chemistry (Weinheim an der Bergstrasse, Germany) · 2018Article
- Density Functional Calculations for Prediction ofACS omega · 2017Article
- Reactivity of hydride bridges in a high-spin [FeChemical science · 2017Article
- Direct amidation of esters with nitroarenes.Nature communications · 2017Article
- Differences between the elimination of early and late transition metals: DFT mechanistic insights into the titanium-catalyzed synthesis of pyrroles from alkynes and diazenes.Chemical science · 2017Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
The use of hydride species for substrate reductions avoids strong reductants, and may enable nitrogenase to reduce multiple bonds without unreasonably low redox potentials. In this work, we explore the N═N bond cleaving ability of a high-spin iron(II) hydride dimer with concomitant release of H2. Specifically, this diiron(II) complex reacts with azobenzene (PhN═NPh) to perform a four-electron reduction, where two electrons come from H2 reductive elimination and the other two come from iron oxidation. The rate law of the H2 releasing reaction indicates that diazene binding occurs prior to H2 elimination, and the negative entropy of activation and inverse kinetic isotope effect indicate that H-H bond formation is the rate-limiting step. Thus, substrate binding causes reductive elimination of H2 that formally reduces the metals, and the metals use the additional two electrons to cleave the N-N multiple bond.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.