ArticleJournal of immunology research2016
In Vitro Effects of Some Botanicals with Anti-Inflammatory and Antitoxic Activity.
Article in Journal of immunology research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 44 citations in OpenAlex.
- Effect of a commercially available fish-based dog food enriched with nutraceuticals on hip and elbow dysplasia in growing Labrador retrievers.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2018Trial
- Effects in dogs with behavioural disorders of a commercial nutraceutical diet on stress and neuroendocrine parameters.The Veterinary record · 2017Trial
- Advances in Functional Pet Food Research: Health-Driven Ingredients, Nutritional Targets and Evidence-Based Claims.Animals : an open access journal from MDPI · 2026Review
- Resolving the "Thick-Wall Challenge" inMicroorganisms · 2026Review
- Screening of Chemical Residues and Antimicrobial Resistance in Dehydrated Chicken Feet Intended as Dog Treats: A Pilot Study.Veterinary medicine international · 2026Article
- Nutraceuticals, Social Interaction, and Psychophysiological Influence on Pet Health and Well-Being: Focus on Dogs and Cats.Veterinary sciences · 2025Review
- Astaxanthin Mitigates 5-Fluorouracil-Induced Hepatotoxicity and Oxidative Stress in Male Rats.Nutrients · 2025Article
- Effects of Heat-Induced Oxidative Stress and Astaxanthin on theCurrent issues in molecular biology · 2024Article
- The role of chamomile oil against ochratoxin A in quail breeders: productive and reproductive performances, egg quality, and blood metabolites.Poultry science · 2024Article
- Adaptive and Innate Cytotoxic Effectors in Chronic Lymphocytic Leukaemia (CLL) Subjects with Stable Disease.International journal of molecular sciences · 2023Article
- Polyphosphate Ester-Type Transporters Improve Antimicrobial Properties of Oxytetracycline.Antibiotics (Basel, Switzerland) · 2023Article
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- Extender Supplementation with Glutathione (GSH) and Taurine ImprovesVeterinary medicine international · 2023Article
- Article
- Evaluation of the efficacy ofDental research journal · 2022Article
- Astaxanthin Mitigates Thiacloprid-Induced Liver Injury and Immunotoxicity in Male Rats.Marine drugs · 2021Article
- A systematic review on the effects ofMetabolism open · 2021Article
- Effect of Chicken Bone Extracts on Metabolic and Mitochondrial Functions of K562 Cell Line.Pharmaceuticals (Basel, Switzerland) · 2020Article
- Impact of Nutritional Supplementation on Canine Dermatological Disorders.Veterinary sciences · 2020Review
- Inhibition of lipopolysaccharide (LPS)-induced neuroinflammatory response by polysaccharide fractions of Khaya grandifoliola (C.D.C.) stem bark, Cryptolepis sanguinolenta (Lindl.) Schltr and Cymbopogon citratus Stapf leaves in raw 264.7 macrophages and U87 glioblastoma cells.BMC complementary and alternative medicine · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several extrinsic factors, like drugs and chemicals, can foster autoimmunity. Tetracyclines, in particular oxytetracycline (OTC), appear to correlate with the emergence of immune-mediated diseases. Accumulation of OTC, the elective drug for gastrointestinal and respiratory infectious disease treatment in broiler chickens, was reported in chicken edible tissues and could represent a potential risk for pets and humans that could assume this antibiotic as residue in meat or in meat-derived byproducts. We investigated the in vitro anti-inflammatory properties of a pool of thirteen botanicals as a part of a nutraceutical diet, with proven immunomodulatory activity. In addition, we evaluated the effect of such botanicals in contrasting the in vitro proinflammatory toxicity of OTC. Our results showed a significant reduction in interferon- (INF-) γ production by human and canine lymphocytes in presence of botanicals ((⁎) p < 0.05). Increased INF-γ production, dependent on 24-hour OTC-incubation of T lymphocytes, was significantly reduced by the coincubation with Haematococcus pluvialis, with Glycine max, and with the mix of all botanicals ((⁎) p < 0.05). In conclusion, the use of these botanicals was shown to be able to contrast OTC-toxicity and could represent a new approach for the development of functional foods useful to enhance the standard pharmacological treatment in infections as well as in preventing or reducing the emergence of inflammatory diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.