ArticleBioMed research international2016
Identification of Secretory Proteins in Mycobacterium tuberculosis Using Pseudo Amino Acid Composition.
Article in BioMed research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed, 127 citations in OpenAlex.
- Comprehensive Approaches to Protein Detection and Analysis in Mycobacterium tuberculosis.Advances in experimental medicine and biology · 2026Review
- Leptospiral imelysin (LIC_10713) is secretory, immunogenic and binds to laminin, fibronectin, and collagen IV.Applied microbiology and biotechnology · 2023Article
- mLoc-mRNA: predicting multiple sub-cellular localization of mRNAs using random forest algorithm coupled with feature selection via elastic net.BMC bioinformatics · 2021Article
- Article
- iBLP: An XGBoost-Based Predictor for Identifying Bioluminescent Proteins.Computational and mathematical methods in medicine · 2021Article
- Prioritizing Disease-Related Microbes Based on the Topological Properties of a Comprehensive Network.Frontiers in microbiology · 2021Article
- Predicting Bacteriophage Enzymes and Hydrolases by Using Combined Features.Frontiers in bioengineering and biotechnology · 2020Article
- ApoPred: Identification of Apolipoproteins and Their Subfamilies With Multifarious Features.Frontiers in cell and developmental biology · 2020Article
- A Brief Survey for MicroRNA Precursor Identification Using Machine Learning Methods.Current genomics · 2020Review
- XG-PseU: an eXtreme Gradient Boosting based method for identifying pseudouridine sites.Molecular genetics and genomics : MGG · 2020Article
- A Linear Regression Predictor for Identifying NMolecular therapy. Nucleic acids · 2019Article
- Meta-4mCpred: A Sequence-Based Meta-Predictor for Accurate DNA 4mC Site Prediction Using Effective Feature Representation.Molecular therapy. Nucleic acids · 2019Article
- iPro70-FMWin: identifying Sigma70 promoters using multiple windowing and minimal features.Molecular genetics and genomics : MGG · 2019Article
- Identification of D Modification Sites by Integrating Heterogeneous Features inMolecules (Basel, Switzerland) · 2019Article
- AOPs-SVM: A Sequence-Based Classifier of Antioxidant Proteins Using a Support Vector Machine.Frontiers in bioengineering and biotechnology · 2019Article
- Application of Machine Learning in Microbiology.Frontiers in microbiology · 2019Review
- AtbPpred: A Robust Sequence-Based Prediction of Anti-Tubercular Peptides Using Extremely Randomized Trees.Computational and structural biotechnology journal · 2019Article
- M6APred-EL: A Sequence-Based Predictor for Identifying N6-methyladenosine Sites Using Ensemble Learning.Molecular therapy. Nucleic acids · 2018Article
- Identifying Phage Virion Proteins by Using Two-Step Feature Selection Methods.Molecules (Basel, Switzerland) · 2018Article
- SeqSVM: A Sequence-Based Support Vector Machine Method for Identifying Antioxidant Proteins.International journal of molecular sciences · 2018Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tuberculosis is killing millions of lives every year and on the blacklist of the most appalling public health problems. Recent findings suggest that secretory protein of Mycobacterium tuberculosis may serve the purpose of developing specific vaccines and drugs due to their antigenicity. Responding to global infectious disease, we focused on the identification of secretory proteins in Mycobacterium tuberculosis. A novel method called MycoSec was designed by incorporating g-gap dipeptide compositions into pseudo amino acid composition. Analysis of variance-based technique was applied in the process of feature selection and a total of 374 optimal features were obtained and used for constructing the final predicting model. In the jackknife test, MycoSec yielded a good performance with the area under the receiver operating characteristic curve of 0.93, demonstrating that the proposed system is powerful and robust. For user's convenience, the web server MycoSec was established and an obliging manual on how to use it was provided for getting around any trouble unnecessary.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.