Trial reportEuropean journal of nuclear medicine and molecular imaging2016
Assessment of the diagnostic accuracy of
Trial report in European journal of nuclear medicine and molecular imaging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- Role ofJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Pooled it
- Meta-analysis of 18F-FDG PET/CT in the diagnosis of infective endocarditis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Pooled it
- New semiquantitative parameters in digital [EJNMMI reports · 2025Article
- The Role of theJournal of personalized medicine · 2024Article
- The clinical value of quantitative cardiovascular molecular imaging: a step towards precision medicine.The British journal of radiology · 2023Review
- FDG PET/CT in Cardiac Infection: Does It Matter? A Narrative Review.Infectious diseases and therapy · 2022Review
- Accuracy ofJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Nuclear Imaging in Infective Endocarditis.Pharmaceuticals (Basel, Switzerland) · 2021Review
- Infective endocarditis in paediatric population.European journal of pediatrics · 2021Review
- Splenic uptake on FDG PET/CT correlates with Kikuchi-Fujimoto disease severity.Scientific reports · 2021Article
- F-18 fluorodeoxyglucose positron emission tomography/computed tomography in the infection of heart.Yeungnam University journal of medicine · 2021Article
- Infected Rastelli Conduit in an Immunocompromised Patient That Was Not Visible on Transthoracic Echocardiogram.CJC open · 2019Article
- Infective endocarditis: innovations in the management of an old disease.Nature reviews. Cardiology · 2019Review
- Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Letter regarding "Meta-analysis of 18F-FDG PET/CT in the diagnosis of infective endocarditis".Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Infections in patients using ventricular-assist devices: Comparison of the diagnostic performance ofJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Cardiac PET/MRI-an update.European journal of hybrid imaging · 2019Review
- Attenuation correction and metal artifact reduction in FDG PET/CT for prosthetic heart valve and cardiac implantable device endocarditis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Standardized uptake values in FDG PET/CT for prosthetic heart valve endocarditis: a call for standardization.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Recommendations on nuclear and multimodality imaging in IE and CIED infections.European journal of nuclear medicine and molecular imaging · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe diagnosis of prosthetic valve (PV) infective endocarditis (IE) and infection of cardiac implantable electronic devices (CIEDs) remains challenging. The aim of this study was to assess the usefulness of
methodsWe included 41 patients suspected of having IE by the Duke criteria who underwent
resultsWe studied 62 areas with suspicion of IE, 28 areas (45 %) showing definite IE and 34 (55 %) showing possible IE. Visual analysis of only AC PET images showed poor diagnostic accuracy (sensitivity 20 %, specificity 57 %). Visual analysis of both AC PET and NAC PET images showed excellent sensitivity (100 %) and intermediate specificity (73 %), focal uptake being more frequently associated with IE. The accuracy of qualitative analysis of NAC PET images depended on the threshold: the maximum sensitivity, specificity and accuracy achieved were 88 %, 80 %, 84 %, respectively. In the semiquantitative analysis of AC PET images, SUVmax was higher in areas of confirmed IE than in those without IE (∆SUVmax 2.2, p < 0.001). When FDG uptake was twice that in the liver, IE was always confirmed, and SUVmax 5.5 was the optimal threshold for IE diagnosis using ROC curve analysis (area under the curve 0.71).
conclusionThe value of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.