Evidence map›Paper›PMID 27596964›Full record

Observational studyThe Journal of emergency medicine2016

Association of Overall Opioid Prescriptions on Adolescent Opioid Abuse.

David C Sheridan, Amber Laurie, Robert G Hendrickson, Rongwei Fu, Bory Kea, B Zane Horowitz

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in The Journal of emergency medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Race Differences in Opioid Misuse and Adolescent Suicidality.Child & adolescent social work journal : C & A · 2022
    Article
  6. Article
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  10. Review
  11. Review
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  16. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

David C SheridanDepartment of Emergency Medicine, Oregon Health and Science University, Portland, Oregon.
Amber LaurieDepartment of Emergency Medicine, Oregon Health and Science University, Portland, Oregon; School of Public Health, Oregon Health and Science University, Portland, Oregon.
Robert G HendricksonDepartment of Emergency Medicine, Oregon Health and Science University, Portland, Oregon; Oregon Poison Center, Oregon Health and Science University, Portland, Oregon.
Rongwei FuDepartment of Emergency Medicine, Oregon Health and Science University, Portland, Oregon; School of Public Health, Oregon Health and Science University, Portland, Oregon.
Bory KeaDepartment of Emergency Medicine, Oregon Health and Science University, Portland, Oregon.
B Zane HorowitzDepartment of Emergency Medicine, Oregon Health and Science University, Portland, Oregon; Oregon Poison Center, Oregon Health and Science University, Portland, Oregon.
Oregon Health & Science University · US

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
Oregon Multidisciplinary Training Program in Emergency Medicine Clinical ResearchK12HL108974 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI NEWGARD, CRAIG D. · 2011 to 2015
$3.8M
NCRR NIH HHS UL1 RR024131NHLBI NIH HHS K12 HL108974
6 · The paper itself

Abstract

backgroundOpioid abuse is a public health epidemic in the United States. Much literature has focused on the prescribing practices of physicians and opioid misuse by adults. However, there are limited data on the effect of opioid prescriptions on adolescent recreational ingestion of these medications.

objectivesThe objective of this study was to assess for a relationship between opioid prescribing practices across the United States and adolescent opioid ingestion calls to poison centers.

methodsThis was an observational study using the National Poison Data System. The study population consisted of poison center calls regarding adolescents between 2005 and 2010 in the database with a coding of "intentional abuse" and an opioid ingestion. National opioid prescription estimates were generated using nationally representative outpatient and inpatient databases.

resultsThere were 4186 adolescent opioid ingestion calls during the study period. There was a general increase between 2005 and 2010 in both teen opioid abuse calls (617 in 2005 to 782 in 2010) and national opioid prescriptions (approximately 78 million in 2005 to 108 million in 2010). For each opioid prescription increase per 100 persons per year, the annual teen opioid abuse calls increased by 1.8% (95% confidence interval 0.9-2.8%), equivalent to an absolute increase of about 0.04 to 0.05 calls per 100,000 teens annually.

conclusionsThere appears to be an association between opioid prescriptions nationally and poison center calls for adolescent opioid ingestions. This is particularly important in this patient population because of impulsivity and early exposure to substance abuse. Providers should be aware of the nonmedical use of opioids by adolescents and educate patients accordingly.

Indexed as

AdolescentAnalgesicsAnalgesics, OpioidFemaleHumansMalePoison Control CentersPoisson DistributionPrescription Drug MisuseRetrospective StudiesUnited StatesYoung AdultAnalgesicsAnalgesics, Opioidadolescentchildingestionmedicineopioid pain

Identifiers

PMID27596964
PMCPMC6212368
OpenAlexW2510740548

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.