Observational studyThe Journal of international medical research2016
Biopsy-proven kidney diseases in the elderly: clinical characteristics, renal histopathological spectrum and prognostic factors.
Observational study in The Journal of international medical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 18 citations in OpenAlex.
- The Spectrum of Biopsy-Proven Renal Diseases in Chinese Elderly Patients and Its Temporal Shift Over 20 Years: A Retrospective Cohort Study.Aging medicine (Milton (N.S.W)) · 2026Article
- Article
- Native kidney biopsies in older adults: disease spectrum, long-term kidney and patient survival and safety.International urology and nephrology · 2022Article
- Clinical Features and Prognosis in ANCA Associated Vasculitis Patients with Acute Kidney Injury.Archives of Iranian medicine · 2022Article
- Nephrotic syndrome in the elderly: epidemiological aspects, clinical data, and renal biopsy findings.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2022Article
- Epidemiological characteristics and pathological changes of primary glomerular diseases.PloS one · 2022Article
- Clinical and pathological analysis of renal biopsies of elderly patients in Northeast China: a single-center study.Renal failure · 2021Article
- Article
- Clinicopathologic features and prognostic factors in older patients with biopsy-proven diabetic nephropathy.International urology and nephrology · 2021Observational
- Pathological spectrum of glomerular disease in patients with renal insufficiency: a single-center study in Northeastern China.Renal failure · 2019Article
- Beyond chronic kidney disease: the diagnosis of Renal Disease in the Elderly as an unmet need. A position paper endorsed by Italian Society of Nephrology (SIN) and Italian Society of Geriatrics and Gerontology (SIGG).Journal of nephrology · 2019Review
- Clinical and Pathological Analysis of 4910 Patients Who Received Renal Biopsies at a Single Center in Northeast China.BioMed research international · 2019Article
- Changes in the Spectrum of Kidney Diseases: An Analysis of 40,759 Biopsy-Proven Cases from 2003 to 2014 in China.Kidney diseases (Basel, Switzerland) · 2018Article
- Kidney Biopsy in 613 Elderly Brazilian Patients: Clinicopathological Correlations.Glomerular diseasesArticle
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Authors and funding
6 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Objective To explore the clinical characteristics, renal histopathological spectrum and prognostic factors of biopsy-proven kidney diseases in the elderly. Methods A retrospective observational study was conducted in elderly patients who had received renal biopsies. Demographic, clinical and pathological data at the time of the biopsy were collected from the medical records. Follow-up records and prognostic factors were studied. Results The elderly (≥60 years) accounted for 74 of 434 (17.1%) native renal biopsies that were performed in a 9-year period. In the cohort of included elderly patients ( n = 72), the prevalence of nephrotic syndrome and acute kidney injury was 62.5% (45 of 72) and 40.3% (29 of 72), respectively. For elderly patients with primary glomerular diseases ( n = 44), membranous nephropathy was the most frequent pathological type (24 of 44; 54.5%). For elderly patients with secondary glomerular diseases ( n = 25), anti-neutrophil cytoplasmic antibody-associated vasculitis was the most frequent aetiology (nine of 25; 36.0%). Requirement for renal replacement therapy (RRT) was an independent risk factor for poor prognosis. Conclusions Kidney diseases in the elderly have distinctive characteristics. Requirement for RRT was associated with poor prognosis in the elderly with biopsy-proven kidney diseases.
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