ArticleBMC cancer2016
Clinically suspected T4 colorectal cancer may be resected using a laparoscopic approach.
Article in BMC cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Laparoscopic surgery for T4 colon cancer: a systematic review and meta-analysis.Surgical endoscopy · 2017Pooled it
- Article
- Benefit of laparoscopic two-team transanal beyond total mesorectal excision for advanced and recurrent rectal cancer with invasion: a retrospective study compared with conventional laparoscopic approach.Techniques in coloproctology · 2025Article
- Does Adjuvant Chemotherapy Benefit Patients with T4 N0 Colon Cancer?Medicina (Kaunas, Lithuania) · 2024Article
- Comparison of clinical efficacy and postoperative inflammatory response between laparoscopic and open radical resection of colorectal cancer.World journal of clinical cases · 2022Article
- Should be a locally advanced colon cancer still considered a contraindication to laparoscopic resection?Surgical endoscopy · 2022Article
- Robotic surgery for clinical T4 rectal cancer: short- and long-term outcomes.Surgical endoscopy · 2022Article
- Prognostic Factors Affecting Disease-Free Survival and Overall Survival in T4 Colon Cancer.Annals of coloproctology · 2021Article
- Feasibility and outcomes of ERAS protocol in elective cT4 colorectal cancer patients: results from a single-center retrospective cohort study.World journal of surgical oncology · 2021Article
- Comparison of Long-Term Survival Outcomes of T4a and T4b Colorectal Cancer.Frontiers in oncology · 2021Article
- Applicability of minimally invasive surgery for clinically T4 colorectal cancer.Scientific reports · 2020Article
- Laparoscopic surgery facilitates administration of adjuvant chemotherapy in locally advanced colon cancer: propensity score analyses.Cancer management and research · 2019Article
- Short- and long-term outcomes following laparoscopicWorld journal of gastroenterology · 2018Article
- Multicentre propensity score-matched analysis of laparoscopic versus open surgery for T4 rectal cancer.Surgical endoscopy · 2017Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe role of laparoscopic resection in patients with clinically suspicious T4 colorectal cancer remains controversial. The aim of this study was to compare the long-term and oncologic outcomes of laparoscopic resection and the open approach in clinical T4 colorectal cancer.
methodsTwo hundred ninety-three consecutive patients undergoing curative surgery for colorectal cancer suspected to be T4 by computed tomography and/or magnetic resonance imaging were reviewed.
resultsDespite clinical suspicion of T4 disease in all cases, concordance with pathologic determination of T4 was only 37.9 %. Of the 71 patients in the laparoscopic group, four (5.6 %) were converted to the open technique. Patients in the laparoscopic group had significantly lower estimated blood loss (p < 0.001), fewer days to first flatus (p = 0.001), shorter length of hospital stay (p < 0.001), and fewer adverse events (14.1 % versus 31.5 %, p = 0.004). After a median follow-up of 36 months, 5-year disease-free survival was not significantly different between the two groups (81.8 % in laparoscopic versus 73.9 % in open surgery, p = 0.433). The clinical factors that predicted T4 staging on pathologic examination were found to be male sex (p = 0.038), preoperative carcinoembryonic antigen status (p = 0.021), clinical N status (p = 0.046), and clinical cancer perforation (p = 0.004).
conclusionsLaparoscopic colorectal resection for T4 colorectal cancer has perioperative and long-term oncologic outcomes similar to those of the open approach when performed by an experienced surgeon.
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