Evidence map›Paper›PMID 27595833›Full record

ArticleDoklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections2016

Effect of pregnancy-specific β1-glycoprotein on indoleamine-2,3-dioxygenase activity in human monocytes.

S A Zamorina, V P Timganova, M S Bochkova, P V Khramtsov, M B Raev

Abstract read
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In one paragraph

Article in Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

S A ZamorinaInstitute of Ecology and Genetics of Microorganisms, Ural Division, Russian Academy of Sciences, Perm, Russia. mantissa7@mail.ru.
V P TimganovaInstitute of Ecology and Genetics of Microorganisms, Ural Division, Russian Academy of Sciences, Perm, Russia.
M S BochkovaInstitute of Ecology and Genetics of Microorganisms, Ural Division, Russian Academy of Sciences, Perm, Russia.
P V KhramtsovPerm State National Research University, Perm, Russia.
M B RaevInstitute of Ecology and Genetics of Microorganisms, Ural Division, Russian Academy of Sciences, Perm, Russia.
Institute of Ecology and Genetics of Microorganisms · RUMoscow Power Engineering Institute · RUUral Federal University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of heterogenic human pregnancy-specific glycoprotein (PSG), obtained by the authors' technology, in the regulation of the indoleamine-2,3-dioxygenase (IDO) activity in female blood monocytes has been studied in vitro. PSG stimulated IDO activity under the conditions of induction of the monocytes by interferon-γ. Upon the induction of cell proliferation by lipopolysaccharides, the stimulating effect was obtained only with 10 μg/mL of PSG. Enhanced IDO activity is probably a factor of peripheral immunological tolerance and antimicrobial protection against intracellular infections in the gestation period.

Indexed as

Immune ToleranceAdultFemaleHumansIndoleamine-Pyrrole 2,3,-DioxygenaseInterferon-gammaLipopolysaccharidesMonocytesPregnancyPregnancy-Specific beta 1-GlycoproteinsIDO1 protein, humanIFNG protein, humanIndoleamine-Pyrrole 2,3,-DioxygenaseInterferon-gammaLipopolysaccharidesPregnancy-Specific beta 1-Glycoproteins

Identifiers

PMID27595833
OpenAlexW2516374389

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.