ArticleDoklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections2016
Myelinated fibers of the mouse spinal cord after a 30-day space flight.
Article in Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Tight Spaces, Tighter Signals: Spatial Constraints as Drivers of Peripheral Myelination.Cells · 2025Article
- Cortical thickness of primary motor and vestibular brain regions predicts recovery from fall and balance directly after spaceflight.Brain structure & function · 2022Article
- Cytoskeleton Markers in the Spinal Cord and Mechanoreceptors of Thick-Toed Geckos after Prolonged Space Flights.Life (Basel, Switzerland) · 2022Article
- Spaceflight-Associated Brain White Matter Microstructural Changes and Intracranial Fluid Redistribution.JAMA neurology · 2019Article
- Bioinformatic Study of Transcriptome Changes in the Mice Lumbar Spinal Cord After the 30-Day Spaceflight and Subsequent 7-Day Readaptation on Earth: New Insights Into Molecular Mechanisms of the Hypogravity Motor Syndrome.Frontiers in pharmacology · 2019Article
- Morphological Study of Myelinated Fibers of the Sciatic Nerve in Mice after Space Flight and Readaptation to the Conditions of Earth Gravity.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2018Article
- Cytoskeleton structure and total methylation of mouse cardiac and lung tissue during space flight.PloS one · 2018Article
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Myelinated fibers and myelin-forming cells in the spinal cord at the L3-L5 level were studied in C57BL/6N mice that had spent 30 days in space. Signs of destruction of myelin in different areas of white matter, reduction of the thickness of myelin sheath and axon diameter, decreased number of myelin-forming cells were detected in "flight" mice. The stay of mice in space during 30 days had a negative impact on the structure of myelinated fibers and caused reduced expression of the markers myelin-forming cells. These findings can complement the pathogenetic picture of the development of hypogravity motor syndrome.
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