ArticleProtein science : a publication of the Protein Society2016
The intervening removable affinity tag (iRAT) production system facilitates Fv antibody fragment-mediated crystallography.
Article in Protein science : a publication of the Protein Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 7 citations in OpenAlex.
- Structure and mechanism of oxalate transporter OxlT in an oxalate-degrading bacterium in the gut microbiota.Nature communications · 2023Article
- Ligand binding to human prostaglandin E receptor EPNature chemical biology · 2019Article
- Structural basis for tumor necrosis factor blockade with the therapeutic antibody golimumab.Protein science : a publication of the Protein Society · 2018Article
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Authors and funding
6 authors at 1 institution in 1 country.
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Abstract
Fv antibody fragments have been used as co-crystallization partners in structural biology, particularly in membrane protein crystallography. However, there are inherent technical issues associated with the large-scale production of soluble, functional Fv fragments through conventional methods in various expression systems. To circumvent these problems, we developed a new method, in which a single synthetic polyprotein consisting of a variable light (V
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Registered trials
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