Evidence map›Paper›PMID 27595676›Full record

Trial reportAmerican heart journal2016

Rationale and design of the Randomized Evaluation of patients with Stable angina Comparing Utilization of noninvasive Examinations (RESCUE) trial.

Arthur E Stillman, Constantine Gatsonis, João A C Lima, William C Black, Jean Cormack, Ilana Gareen, Udo Hoffmann, Tao Liu, Kreton Mavromatis, Mitchell D Schnall and 2 more

Abstract readClinical Trial, Phase IIIComparative StudyMulticenter Study
In one paragraph

Trial report in American heart journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Update of the Brazilian Guideline on Nuclear Cardiology - 2020.Arquivos brasileiros de cardiologia · 2020
    Guideline
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Arthur E StillmanDepartment of Radiology and Imaging Sciences, Emory University, 1365 Clifton Rd NE Atlanta, GA 30322; Division of Cardiology, Emory University, Atlanta GA. Electronic address: aestill@emory.edu.
Constantine GatsonisCenter for Statistical Sciences, Brown University, Providence RI; Department of Biostatistics, Brown University School of Public Health, Providence RI.
João A C LimaDepartments of Medicine and Radiology, Johns Hopkins University, Baltimore MD.
William C BlackDepartment of Radiology, Dartmouth-Hitchcock Medical Center, Lebanon NH.
Jean CormackCenter for Statistical Sciences, Brown University, Providence RI.
Ilana GareenCenter for Statistical Sciences, Brown University, Providence RI; Department of Epidemiology, Brown University School of Public Health.
Udo HoffmannDepartment of Radiology, Massachusetts General Hospital, Boston MA.
Tao LiuCenter for Statistical Sciences, Brown University, Providence RI; Department of Biostatistics, Brown University School of Public Health, Providence RI.
Kreton MavromatisDivision of Cardiology, Emory University, Atlanta GA.
Mitchell D SchnallDepartment of Radiology, University of Pennsylvania, Philadelphia PA.
James E UdelsonDivision of Cardiology, Tufts-New England Medical Center, Boston MA.
Pamela K WoodardDepartment of Radiology, Mallinckrodt Institute of Radiology, Washington University, St. Louis MO.

Funding

RESCUE: Randomized Evaluation of Patients with Stable Angina Comparing UtilizatioR01HS019403 · AHRQ · AMERICAN COLLEGE OF RADIOLOGY · PI STILLMAN, ARTHUR E · 2010 to 2010
$9.7M
AHRQ HHS R01 HS019403
6 · The paper itself

Abstract

RESCUE is a phase III, randomized, controlled, multicenter, comparative efficacy study, designed to compare two diagnostic imaging/treatment paradigms that use coronary computed tomography angiography (CCTA) or single photon emission computed tomography myocardial perfusion imaging (SPECT MPI) for assisting in the diagnosis of ischemic heart disease in patients with stable angina symptoms, and guiding subsequent treatment. The study is based on the hypothesis that CCTA as a diagnostic tool is associated with no increase in cardiac risk, decreased cost, and reduced radiation exposure compared with SPECT MPI. The RESCUE trial was funded by the Agency for Healthcare Research and Quality (AHRQ) and the American College of Radiology Imaging Network (ACRIN) Fund for Imaging Innovation, began in 2011, and completed in 2014.

Indexed as

Computed Tomography AngiographyCoronary AngiographyMyocardial Perfusion ImagingTomography, Emission-Computed, Single-PhotonAdrenergic beta-AntagonistsAdultAgedAged, 80 and overAngina, StableAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsAntihypertensive AgentsDiet TherapyExerciseFemaleHeart DiseasesAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsAntihypertensive AgentsHydroxymethylglutaryl-CoA Reductase InhibitorsPlatelet Aggregation InhibitorsVasodilator Agents

Identifiers

PMID27595676
PMCPMC5443342

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.