ArticleTherapeutic advances in respiratory disease2016
Uncontrolled asthma and its risk factors in adult Chinese asthma patients.
Article in Therapeutic advances in respiratory disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Pooled it
- Effects of omalizumab on lung function in patients with moderate-to-severe allergic asthma: a systematic review and meta-analysis.Therapeutic advances in respiratory diseasePooled it
- Uncontrolled Status, Disease Burden, and Associated Risk Factors Among Patients with Asthma Receiving Medium-to-High Dose ICS or ICS/LABA: A Retrospective Analysis.Advances in therapy · 2026Observational
- Article
- Analysis and mining of Dupilumab adverse events based on FAERS database.Scientific reports · 2025Article
- The association between waist circumference and adult asthma attack using nationally representative samples.BMC public health · 2024Article
- Risk Factors Associated with Asthma Control and Quality of Life in Patients with Mild Asthma Without Preventer Treatment, a Cross-Sectional Study.Journal of asthma and allergy · 2024Article
- Disease Burden, Treatment Patterns and Asthma Control in Adult Patients with Asthma in China: A Real-World Study.Journal of asthma and allergy · 2024Article
- Review
- Temporal trend in burden of asthma in China, South Korea, and Japan, 1990-2019: results from the Global Burden of Disease Study 2019.Journal of thoracic disease · 2023Article
- Factors associated with uncontrolled asthma among adult asthmatic patients in eastern Ethiopia: A multicenter study.SAGE open medicine · 2022Article
- INITIAL - An observational study of disease severity in newly diagnosed asthma patients and initial response following 12 weeks' treatment.Scientific reports · 2019Observational
- Disease burden and eosinophilic phenotype in Chinese patients with moderate-to-severe asthma: Baseline analysis of a prospective, multicenter study (PRESENT).Therapeutic advances in respiratory diseaseObservational
- Short-acting beta-2 agonist prescription patterns and clinical outcomes in Chinese patients with asthma: an observational study in mainland China for the SABINA programme.Therapeutic advances in respiratory diseaseObservational
- CARE: an observational study of adherence to home nebulizer therapy among children with asthma.Therapeutic advances in respiratory diseaseObservational
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAsthma affects a large number of patients in China, but relatively little is known about asthma management among Chinese patients. This study aims to estimate asthma control rate among adult Chinese patients and to identify predictors associated with uncontrolled asthma.
methodsA total of 4125 asthma patients aged ⩾17 years and representing all regions of mainland China except Tibet were surveyed. Asthma control status was assessed using the Asthma Control Test (ACT) and classified as controlled (ACT score ⩾ 20) and uncontrolled (ACT score ⩽ 19). A multivariate logistic regression model was used to identify predictors associated with uncontrolled asthma from the factors including demographics, rhinitis, allergic rhinitis, and treatment adherence.
resultsAsthma was controlled in 44.9%, and uncontrolled in 55.1% of the study participants. High rates of uncontrolled asthma were found in patients with treatment nonadherence (77.3%), poor adherence (66.2%), no schooling (64.8%), or obesity (62.9%). The risk of uncontrolled asthma was much higher in the treatment nonadherence group than the complete adherence group [odds ratio (OR) = 4.55 (3.68-5.62), p < 0.001]. Other predictors for uncontrolled asthma included concomitant rhinitis [OR = 1.31 (1.14-1.50), p < 0.001], obesity [OR = 1.31 (1.05-1.64), p = 0.019], asthma duration > 3 years [OR = 1.22 (1.07-1.39), p = 0.004] and age ⩾ 45 years [OR = 1.23 (1.07-1.41), p = 0.004].
conclusionsAbout half of the participants in this study had uncontrolled asthma. Treatment nonadherence is one of the significant predictors, which is very strongly associated with uncontrolled asthma. Efforts should be prioritized to promote patients' treatment adherence to improve asthma control while attention is needed on rhinitis or obesity.
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