ArticleNature materials2017
Porous microwells for geometry-selective, large-scale microparticle arrays.
Article in Nature materials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Solvent-triggered reconfiguration of optical physical unclonable functions.Nature communications · 2026Article
- Rapid and Controllable Multilayer Cell Sheet Assembly via Biodegradable Nanochannel Membranes.Advanced functional materials · 2025Article
- Random fractal-enabled physical unclonable functions with dynamic AI authentication.Nature communications · 2023Article
- Encoding microcarriers for biomedicine.Smart medicine · 2023Review
- Article
- Article
- Rapid fabrication of sieved microwells and cross-flow microparticle trapping.Scientific reports · 2020Article
- Edible unclonable functions.Nature communications · 2020Article
- Spatially resolved and multiplexed MicroRNA quantification from tissue using nanoliter well arrays.Microsystems & nanoengineering · 2020Article
- Defining Cell Cluster Size by Dielectrophoretic Capture at an Array of Wireless Electrodes of Several Distinct Lengths.Micromachines · 2019Article
- Geometric Effect for Biological Reactors and Biological Fluids.Bioengineering (Basel, Switzerland) · 2018Review
- Microstencil-based spatial immobilization of individual cells for single cell analysis.Biomicrofluidics · 2018Article
- Low temperature flow lithography.Biomicrofluidics · 2018Article
- Quantitative and multiplex microRNA assays from unprocessed cells in isolated nanoliter well arrays.Lab on a chip · 2018Article
- Recent Advances in Engineering the Stem Cell Microniche in 3D.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2018Review
- Large-scale patterning of living colloids for dynamic studies of neutrophil-microbe interactions.Lab on a chip · 2018Article
- ELIPatch, a thumbnail-size patch with immunospot array for multiplexed protein detection from human skin surface.Biomicrofluidics · 2018Article
- Microfluidic platform for selective microparticle parking and paired particle isolation in droplet arrays.Biomicrofluidics · 2018Article
- Methods of Micropatterning and Manipulation of Cells for Biomedical Applications.Micromachines · 2017Review
- Microparticle parking and isolation for highly sensitive microRNA detection.Lab on a chip · 2017Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Large-scale microparticle arrays (LSMAs) are key for material science and bioengineering applications. However, previous approaches suffer from trade-offs between scalability, precision, specificity and versatility. Here, we present a porous microwell-based approach to create large-scale microparticle arrays with complex motifs. Microparticles are guided to and pushed into microwells by fluid flow through small open pores at the bottom of the porous well arrays. A scaling theory allows for the rational design of LSMAs to sort and array particles on the basis of their size, shape, or modulus. Sequential particle assembly allows for proximal and nested particle arrangements, as well as particle recollection and pattern transfer. We demonstrate the capabilities of the approach by means of three applications: high-throughput single-cell arrays; microenvironment fabrication for neutrophil chemotaxis; and complex, covert tags by the transfer of an upconversion nanocrystal-laden LSMA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.